Nivinskaia M M, Ratner T G, Kondrat'eva A P, Plastova N F, Bel'ter S A
Vopr Onkol. 1977;23(5):35-40.
The results of radiation therapy in 800 patients with lung metastases of different malignant neoplasms are reported. Metastases were multiple--in 53 cases, single--in 7, solitory--in 14. In 6 patients metastatic nodes were noted in the pleura. Total irradiation was employed (of one lung in 36 patients, of both lungs--in 44). In 15 patients an additional local irradiation of separate metastatic foci was performed. As a result of the treatment an immediate objective effect was gained in 44 of 80 patients (55%), metastases completely disappeared in 12 cases (15%). The period of remission ranged from 1 month to 2.5 years, making 8 months on the average. The data obtained indicate the rationality to further improve the technic concerned and to study simultaneously the opportunities of using radiotherapy, supplemented with the use of different antitumor drugs, taking into account the sensitivity of some or other malignant tumor to them.
报告了800例不同恶性肿瘤肺转移患者的放射治疗结果。转移灶为多发的53例,单发的7例,孤立性的14例。6例患者胸膜有转移结节。采用全肺照射(36例照射一侧肺,44例照射双侧肺)。15例患者对单个转移灶进行了额外的局部照射。治疗结果显示,80例患者中有44例(55%)立即获得客观疗效,12例(15%)转移灶完全消失。缓解期为1个月至2.5年,平均8个月。所获数据表明,进一步改进相关技术并同时研究使用放疗联合不同抗肿瘤药物的机会是合理的,要考虑到某些恶性肿瘤对这些药物的敏感性。