芬苯达唑对控制小马未成熟圆线虫感染的疗效。

The efficacy of fenbendazole in the control of immature strongyle infections in ponies.

作者信息

Duncan J L, McBeath D G, Best J M, Preston N K

出版信息

Equine Vet J. 1977 Jul;9(3):146-9. doi: 10.1111/j.2042-3306.1977.tb04007.x.

DOI:10.1111/j.2042-3306.1977.tb04007.x

Abstract

The efficacy of fenbendazole against immature stages of Trichonema spp., Strongylus vulgaris and Strongylus edentatus was evaluated. Naturally infected 6 to 12 month old ponies were given single, oral doses of 0, 15, 30 and 60 mg/kg of body weight. A dose response relationship was noted between increasing dose levels and efficiency against larval trichonemes and migrating stages of S. vulgaris and S. edentatus. Dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of Trichonema spp., while doses of 60 mg/kg removed 83 per cent and 89 per cent of the migrating larvae of S. vulgaris and S. edentatus respectively.

摘要

评估了芬苯达唑对毛圆线虫属未成熟阶段、普通圆线虫和无齿圆线虫的疗效。给自然感染的6至12月龄小马单次口服0、15、30和60毫克/千克体重的剂量。在剂量水平增加与对幼虫毛圆线虫以及普通圆线虫和无齿圆线虫移行阶段的效力之间发现了剂量反应关系。30毫克/千克及更高的剂量水平清除了93%的毛圆线虫属黏膜阶段，而60毫克/千克的剂量分别清除了83%的普通圆线虫和89%的无齿圆线虫移行幼虫。