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风疹病毒RA 27/3株未能诱导内在干扰。

Failure of the RA 27/3 strain of rubella virus to induce intrinsic interference.

作者信息

Kleiman M B, Carver D H

出版信息

J Gen Virol. 1977 Aug;36(2):335-40. doi: 10.1099/0022-1317-36-2-335.

Abstract

Unlike other strains tested, the RA 27/3 vaccine strain of rubella virus, attenuated in human fibroblasts, failed to inhibit superinfection with Newcastle disease virus (i.e. induce intrinsic interference). Since proteins of the input virion are known to lead to intrinsic interference, these may differ in the RA 27/3 strain from those in other rubella strains.

摘要

与其他测试菌株不同,在人成纤维细胞中减毒的风疹病毒RA 27/3疫苗株未能抑制新城疫病毒的超感染(即诱导内在干扰)。由于已知输入病毒体的蛋白质会导致内在干扰,因此RA 27/3株中的这些蛋白质可能与其他风疹株中的不同。

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