抗肿瘤剂XXIII：土木香内酯，一种来自玉山香青的抗肿瘤成分。
Antitumor agents XXIII: Helenalin, and antitumor principle from Anaphalis morrisonicola HAY.
作者信息
Lee K H, Haruna M, Huang H C, Wu B S, Hall I H
出版信息
J Pharm Sci. 1977 Aug;66(8):1194-5. doi: 10.1002/jps.2600660836.
PMID:561183
Abstract
A chloroform extract of the whole plant of Anaphalis morrisonicola HAY, showed significant antitumor activity against Ehrlich ascites carcinoma, Walker 256 carcinosarcoma, and P-388 lymphocytic leukemia. Systematic fractionation of the extract led to isolation and characterization of helenalin, a pseudoguaianolide, as the major active principle.
摘要
玉山香青全株的氯仿提取物对艾氏腹水癌、沃克256癌肉瘤和P - 388淋巴细胞白血病显示出显著的抗肿瘤活性。对该提取物进行系统分离，得到了一种假愈创木烷型倍半萜内酯——堆心菊灵，并将其鉴定为主要活性成分。
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