雄性大鼠促卵泡激素（FSH）的昼夜变化

Diurnal variation of follicle stimulating hormone (FSH) in the male rat.

作者信息

McLean B K, Rubel A, Nikitovitch-Winer M B

出版信息

Neuroendocrinology. 1977;23(1):23-30. doi: 10.1159/000122651.

Abstract

The phenomenon of diurnal variation in secretion of FSH, LH and prolactin (Prl) has been investigated in adult male Wistar rats. When these animals were decapitated at 2 h intervals throughout the 24 h day, a highly significant elevation of serum FSH was observed at 12.30 and 14.30 h. No definite diurnal pattern was observed for LH and Prl. The basic FSH rhythm was found to persist in animals bled via an indwelling atrial cannula or by cardiac puncture. However, these techniques of blood collection were found to produce some variation in the timing of the surge. These observations suggest the existence of diurnal variation in the secretion of FSH in the adult male rat.

摘要

在成年雄性Wistar大鼠中研究了促卵泡激素（FSH）、促黄体生成素（LH）和催乳素（Prl）分泌的昼夜变化现象。当在24小时内每隔2小时将这些动物断头时，在12:30和14:30观察到血清FSH显著升高。未观察到LH和Prl有明确的昼夜模式。发现通过留置心房插管或心脏穿刺采血的动物中，FSH的基本节律持续存在。然而，发现这些采血技术在高峰出现的时间上会产生一些变化。这些观察结果表明成年雄性大鼠中FSH分泌存在昼夜变化。