Schwarz R, Retzke U, Barten G
Zentralbl Gynakol. 1977;99(10):618-24.
By means of quantitative sphygmometry and the unbloody recording of arterial blood pressure the hemodynamic effect of an infusion of 500 ml dextrane 75 (Infukoll 6%) on the cardiovascular systeme in 10 normovolemic normotensive healthy late pregnant women is examined. Hematocrit decreases as an expression of increasing plasma volume. Arterial blood pressure and heart rate remain unchanged. Stroke volume and cardiac output increase significantly. Simultaneously total peripheral resistance decreases. Therefore dextrane 75 is indicated in pregnancy for therapy and prophylaxis of circulatory conditions with lowered plasma volume.
通过定量血压测量法和无创记录动脉血压,研究了在10名血容量正常、血压正常的健康晚期孕妇中,静脉输注500毫升75右旋糖酐(英孚可6%)对心血管系统的血液动力学影响。血细胞比容降低,表明血浆量增加。动脉血压和心率保持不变。每搏输出量和心输出量显著增加。同时,总外周阻力降低。因此,75右旋糖酐适用于孕期治疗和预防血浆量降低的循环系统疾病。