Robbins N, Szilagyi G, Tanowitz H B, Luftschein S, Baum S G
Arch Intern Med. 1977 Sep;137(9):1171-4.
Three patients with endocarditis caused by Streptococcus mutans were seen during a six-month period. All had clinical features of subacute bacterial endocarditis, including fever, heart murmurs, and positive blood cultures. One had underlying aortic insufficiency and two had idiopathic hypertrophic subaortic stenosis. All patients were treated with parenteral antibiotics and were cured. Streptococcus mutans is a pleomorphic, microaerophilic organism that is associated with dental caries and plaque. Differentiation of S mutans from enterococcal endocarditis is important because the former condition can be treated for a shorter period of time with penicillin alone, without the addition of aminoglycoside antibiotics.
在六个月期间内，共发现3例由变形链球菌引起的心内膜炎患者。所有患者均有亚急性细菌性心内膜炎的临床特征，包括发热、心脏杂音和血培养阳性。1例患者有潜在的主动脉瓣关闭不全，2例有特发性肥厚性主动脉瓣下狭窄。所有患者均接受了胃肠外抗生素治疗并治愈。变形链球菌是一种多形性、微需氧菌，与龋齿和牙菌斑有关。将变形链球菌引起的心内膜炎与肠球菌性心内膜炎区分开来很重要，因为前者单用青霉素治疗较短时间即可，无需加用氨基糖苷类抗生素。
