Keenan W J, Steichen J J, Mahmood K, Altshuler G
Am J Dis Child. 1977 Nov;131(11):1224-7. doi: 10.1001/archpedi.1977.02120240042009.
The usefulness of the microscopic examination of the placenta, associated membranes, and umbilical cord was tested in a retrospective clinical review. Fifty-nine patients with inflammation were matched by sex, race, and gestation with 59 patients without inflammation. Blind review of the clinical course of these infants revealed five cases of culture-positive septicemia, 28 cases of probable sepsis, 39 cases of possible sepsis, and 46 normal infants. The clinical categorization was significantly correlated with the microscopic appearance of the placenta, membranes, and cord. Triple vessel vasculitis in the umbilical cord vessels and chorionic microabscesses were significantly related to the incidence of proven, probable, and possible clinical sepsis. The microscopic examination of the umbilical cord and placenta provides a useful, but not infallible, tool in the evaluation of sepsis in the newly born infant.
在一项回顾性临床研究中，对胎盘、胎膜及脐带进行显微镜检查的实用性进行了测试。59例有炎症的患者与59例无炎症的患者按性别、种族和孕周进行匹配。对这些婴儿临床病程的盲法评估显示，有5例血培养阳性败血症、28例可能的败血症、39例疑似败血症以及46例正常婴儿。临床分类与胎盘、胎膜和脐带的显微镜表现显著相关。脐带血管的三血管血管炎和绒毛微脓肿与已证实、可能及疑似临床败血症的发生率显著相关。脐带和胎盘的显微镜检查在评估新生儿败血症方面提供了一种有用但并非绝对可靠的工具。
