Woodhouse N J, Chalmers A H, Wells I P, Dewbury K C, Mohamedally S M
Br J Radiol. 1977 Oct;50(598):699-705. doi: 10.1259/0007-1285-50-598-699.
Radiological observations over two years were made in 23 patients with Paget's disease. Radiological criteria for progression and regression of disease are defined. Fourteen of the patients were treated with salmon calcitonin. Of these treated patients four showed regression of the disease and only two showed progression, both in the skull vault. Of the remaining nine untreated patients none showed regression but two showed progression. The radiological findings confirm that calcitonin will prevent the extension and sometimes induce healing of Paget's disease in long bones but that the skull appears to respond differently. Radiological changes were slow to occur and yearly or two yearly follow up is sufficient.
对23例佩吉特病患者进行了为期两年的放射学观察。定义了疾病进展和消退的放射学标准。14例患者接受了鲑鱼降钙素治疗。在这些接受治疗的患者中，4例疾病出现消退，仅2例出现进展，且均在颅顶。其余9例未治疗的患者中，无1例出现消退，但有2例出现进展。放射学检查结果证实，降钙素可防止佩吉特病在长骨中扩展，有时还可促使其愈合，但颅骨的反应似乎有所不同。放射学变化出现缓慢，每年或每两年进行一次随访就足够了。
