有机磷抑制的乙酰胆碱酯酶复活剂的构效关系。XI-β-(4-吡啶基)丙烯醛肟的双季铵化合物
Structure-activity relationships in reactivators of organophosphorus-inhibited acetylcholinesterase. XI - Bisquaternary compounds of beta-(4-pyridyl)acraldoxime.
作者信息
Antonini I, Cristalli G, Franchetti P, Grifantini M, Martelli S
出版信息
Farmaco Sci. 1977 Dec;32(12):905-8.
PMID:563345
Abstract
Several bisquaternary salts of beta-(4-pyridyl)acraldoxime were prepared and tested for their reactivating potency on phosphorylated electric eel cholinesterase. The in vitro testing revealed that the new compounds have little to no effects.
摘要
制备了几种β-(4-吡啶基)丙烯醛肟的双季铵盐，并测试了它们对磷酸化电鳗胆碱酯酶的复活效力。体外测试表明，这些新化合物几乎没有影响。
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