Gordon A M
J Int Med Res. 1977;5 Suppl 4:81-4.
The author outlines the hypothesis of the role of amines in depression. Postulating that depression involves a derangement of amine metabolism in which a deficit of amine activity occurs in certain areas of the brain which in turn results in altered transmission, the theory proposes that certain antidepressant drugs effect an elevation of brain amines restoring normal transmission and relieving the depression.
作者概述了胺类物质在抑郁症中作用的假说。该理论假定抑郁症涉及胺类物质代谢紊乱，即大脑某些区域胺类活性不足，进而导致神经传递改变，某些抗抑郁药物可提高大脑胺类物质水平，恢复正常神经传递并缓解抑郁症状。
