须发癣菌的细胞外胶原酶
Extracellular collagenase from Trichophyton schoenleinii.
作者信息
Rippon J W
出版信息
J Bacteriol. 1968 Jan;95(1):43-6. doi: 10.1128/jb.95.1.43-46.1968.
Abstract
The dermatophyte Trichophyton schoenleinii elaborates an extracellular collagenase which is specific for native collagen and gelatin and is separable from an enzyme which is active against Azocoll. The fungal enzyme differs from the bacterial collagenases in its acid pH and small molecular weight. In addition, the fungal enzyme is irreversibly inhibited by ethylenediaminetetraacetic acid, whereas the bacterial enzymes can be restored by divalent cations, such as Mg(++) and Ca(++).
摘要
须癣毛癣菌能产生一种细胞外胶原酶，该酶对天然胶原蛋白和明胶具有特异性，并且可与一种对偶氮胶原具有活性的酶分离。这种真菌酶在酸性pH值和小分子量方面与细菌胶原酶不同。此外，这种真菌酶会被乙二胺四乙酸不可逆地抑制，而细菌酶可被二价阳离子如Mg(++)和Ca(++)恢复活性。
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