出血对小猫和猫的血红蛋白浓度、血容量及动脉压的影响。

The effect of haemorrhage on haemoglobin concentration, blood volume and arterial pressure in kittens and cats.

作者信息

Mott J C

出版信息

J Physiol. 1968 Feb;194(3):659-67. doi: 10.1113/jphysiol.1968.sp008431.

DOI:10.1113/jphysiol.1968.sp008431

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1365659/

Abstract

The arterial haemoglobin concentration in kittens less than 24 hr old was inversely related to body weight. There was about twice as much haemoglobin/unit body weight at birth as in adult cats. Haemoglobin concentrations were minimal at 3-6 weeks of age.2. In animals lightly anaesthetized with sodium pentobarbitone, arterial pressure rose from 52 mm Hg at birth in kittens to 133 mm Hg in adult cats. Blood volume decreased from 73 ml./kg at birth to 60 ml./kg in adults.3. When kittens less than a fortnight old were subjected to stepwise blood letting, arterial pressure fell proportionately with blood volume; in older kittens and in cats, arterial pressure was less well maintained at similar proportionate reductions of blood volume than in young kittens.4. The responses to haemorrhage of kittens and cats were compared with those of rabbits similarly treated and with those of adult cats anaesthetized with urethane and chloralose reported in the literature.

摘要

出生不到24小时的小猫动脉血红蛋白浓度与体重呈负相关。出生时每单位体重的血红蛋白量约为成年猫的两倍。血红蛋白浓度在3至6周龄时最低。
在用戊巴比妥钠轻度麻醉的动物中，小猫出生时的动脉压为52毫米汞柱，成年猫为133毫米汞柱。血容量从出生时的73毫升/千克降至成年时的60毫升/千克。
对出生不到两周的小猫进行逐步放血时，动脉压随血容量成比例下降；在年龄较大的小猫和成年猫中，血容量以相似比例减少时，动脉压维持得不如幼小猫好。
将小猫和成年猫对出血的反应与同样处理的兔子以及文献中报道的用氨基甲酸乙酯和氯醛糖麻醉的成年猫的反应进行了比较。