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Strips of smooth muscle from common carotid arteries of sheep were electrically quiescent in solution containing Na 148 mM and Ca 2.5 mM.2. When Ca was removed they became electrically active. Addition of low concentrations of Ca (0.025-0.075 mM) or Mg (0.025-0.750 mM) stopped their activity while ethylenediamine tetra-acetate (EDTA) (1.25 mM) accelerated it.3. Replacement of Na by Tris or choline stopped the activity in Ca-free solution. After partial replacement of Na electrical activity could be restored by lowering the resting potential but after complete replacement of Na it could not.4. In the presence of Ca (2.5 mM) small spikes could sometimes be induced after 20 min in Na-free Tris solution by lowering the resting potential by an increase in the external K concentration.5. The results indicate that the depolarizing current of action potentials in this smooth muscle was largely carried by Na, although a little may have been carried by Ca in Ca-containing solutions.6. The arteries in general resembled striated muscle rather than intestinal smooth muscle in these respects, but unlike striated muscle their action potentials were not stopped by tetrodotoxin.

从绵羊颈总动脉获取的平滑肌条在含有148 mM钠和2.5 mM钙的溶液中呈电静息状态。
去除钙后它们变得电活跃。添加低浓度的钙（0.025 - 0.075 mM）或镁（0.025 - 0.750 mM）会停止其活动，而乙二胺四乙酸（EDTA）（1.25 mM）会加速其活动。
用 Tris 或胆碱替代钠会使无钙溶液中的活动停止。部分替代钠后，通过降低静息电位可恢复电活动，但完全替代钠后则不能。
在含有2.5 mM钙的情况下，在无钠的Tris溶液中，有时通过增加细胞外钾浓度降低静息电位，20分钟后可诱导出小的尖峰。
结果表明，这种平滑肌动作电位的去极化电流主要由钠携带，尽管在含钙溶液中可能有少量由钙携带。
在这些方面，动脉总体上更类似于横纹肌而非肠道平滑肌，但与横纹肌不同的是，它们的动作电位不会被河豚毒素阻断。

Strips of smooth muscle from common carotid arteries of sheep were electrically quiescent in solution containing Na 148 mM and Ca 2.5 mM.2. When Ca was removed they became electrically active. Addition of low concentrations of Ca (0.025-0.075 mM) or Mg (0.025-0.750 mM) stopped their activity while ethylenediamine tetra-acetate (EDTA) (1.25 mM) accelerated it.3. Replacement of Na by Tris or choline stopped the activity in Ca-free solution. After partial replacement of Na electrical activity could be restored by lowering the resting potential but after complete replacement of Na it could not.4. In the presence of Ca (2.5 mM) small spikes could sometimes be induced after 20 min in Na-free Tris solution by lowering the resting potential by an increase in the external K concentration.5. The results indicate that the depolarizing current of action potentials in this smooth muscle was largely carried by Na, although a little may have been carried by Ca in Ca-containing solutions.6. The arteries in general resembled striated muscle rather than intestinal smooth muscle in these respects, but unlike striated muscle their action potentials were not stopped by tetrodotoxin.

从绵羊颈总动脉获取的平滑肌条在含有148 mM钠和2.5 mM钙的溶液中呈电静息状态。
去除钙后它们变得电活跃。添加低浓度的钙（0.025 - 0.075 mM）或镁（0.025 - 0.750 mM）会停止其活动，而乙二胺四乙酸（EDTA）（1.25 mM）会加速其活动。
用 Tris 或胆碱替代钠会使无钙溶液中的活动停止。部分替代钠后，通过降低静息电位可恢复电活动，但完全替代钠后则不能。
在含有2.5 mM钙的情况下，在无钠的Tris溶液中，有时通过增加细胞外钾浓度降低静息电位，20分钟后可诱导出小的尖峰。
结果表明，这种平滑肌动作电位的去极化电流主要由钠携带，尽管在含钙溶液中可能有少量由钙携带。
在这些方面，动脉总体上更类似于横纹肌而非肠道平滑肌，但与横纹肌不同的是，它们的动作电位不会被河豚毒素阻断。

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