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In vitro response of the bovine peripheral lymphocyte to stimulation with cellular antigens of group B streptococcus and phytohaemagglutinin.牛外周血淋巴细胞对B族链球菌细胞抗原和植物血凝素刺激的体外反应。
Immunology. 1968 Feb;14(2):175-80.
2
Cellular and antibody reactions to streptococcal M protein types 1, 3, 6 and 12.针对1、3、6和12型链球菌M蛋白的细胞和抗体反应
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3
[Cellular immunity in hepatopathies: stimulation in vitro of lymphocytes with hepatic antigens].
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4
Effect of Staphylococcus aureus and Streptococcus uberis on apoptosis of bovine mammary gland lymphocytes.金黄色葡萄球菌和乳房链球菌对牛乳腺淋巴细胞凋亡的影响。
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Macrophage-lymphocyte interaction in the antigen-induced blastogenic response of human peripheral blood leukocytes.巨噬细胞与淋巴细胞在人外周血白细胞抗原诱导的增殖反应中的相互作用。
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Graft reaction in tissue culture. 3. Effect of phytohaemagglutinin.组织培养中的移植反应。3. 植物血凝素的作用。
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A passive hemagglutination technique for detection of Streptococcus dysgalactiae antibody.一种用于检测停乳链球菌抗体的被动血凝技术。
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Expression of lymphocyte homing and adhesion molecules during intramammary infection of cows with Serratiamarcescens or Streptococcusuberis: correlation with bacterial colonization and clinical signs.乳房内感染粘质沙雷氏菌或乳房链球菌的奶牛淋巴细胞归巢及黏附分子的表达：与细菌定植及临床症状的相关性
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Experimental myocarditis: in vitro and in vivo studies of lymphocytes sensitized to heart extracts and group A streptococci.实验性心肌炎：对心脏提取物和A组链球菌致敏淋巴细胞的体外和体内研究
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ANTIBODIES AGAINST STREPTOCOCCUS AGALACTIAE IN THE COLOSTRUM OF FIRST-CALF HEIFERS.初产母牛初乳中抗无乳链球菌的抗体
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DOSE-RESPONSE CURVE OF PHYTOHAEMAGGLUTININ IN TISSUE CULTURE OF NORMAL HUMAN LEUCOCYTES.正常人白细胞组织培养中植物血凝素的剂量反应曲线
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Fluorescence microscopy in exfoliative cytology. Report of acridine orange examination of 5491 cases, with comparison by the Papanicolaou technic.脱落细胞学中的荧光显微镜检查。5491例吖啶橙检查报告，并与巴氏技术作比较。
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Bovine staphylococcic mastitis: an immunohistochemical study of the cellular sites of antibody formation.牛葡萄球菌性乳腺炎：抗体形成细胞位点的免疫组织化学研究
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Cross-reactive antigen shared by Streptococcus agalactiae and certain bovine tissues.无乳链球菌与某些牛组织共有的交叉反应性抗原。
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牛外周血淋巴细胞对B族链球菌细胞抗原和植物血凝素刺激的体外反应。

In vitro response of the bovine peripheral lymphocyte to stimulation with cellular antigens of group B streptococcus and phytohaemagglutinin.

作者信息

Kelly R H

出版信息

Immunology. 1968 Feb;14(2):175-80.

PMID:5640943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1409288/
Abstract

This investigation was conducted in two parts: first establishing separatory and cultural procedures for bovine lymphocytes, and then studying the response of these cells following stimulation with phytohaemagglutinin (PHA) and cellular constituents of . Peripheral lymphocytes from normal animals, those with chronic udder infections, and animals hyperimmunized with cellular constituents of were studied. The bovine lymphocyte responded to PHA with blastogenic changes similar to those of the human lymphocyte. No changes in cellular morphology or cytochemistry were detected following stimulation with cell antigens of Lymphocytes from hyperimmunized animals were shown to be capable of transformation in response to a different antigenic stimulation. Several explanations for this immunological inertia are presented.

摘要

本研究分两部分进行

首先建立牛淋巴细胞的分离和培养程序，然后研究这些细胞在用植物血凝素（PHA）和[具体物质]的细胞成分刺激后的反应。对来自正常动物、患有慢性乳房感染的动物以及用[具体物质]的细胞成分进行超免疫的动物的外周淋巴细胞进行了研究。牛淋巴细胞对PHA的反应表现出与人类淋巴细胞相似的致有丝分裂变化。在用[具体物质]的细胞抗原刺激后，未检测到细胞形态或细胞化学的变化。超免疫动物的淋巴细胞显示能够对不同的抗原刺激做出转化反应。针对这种免疫惰性提出了几种解释。