Wunderlich M
Arch Geschwulstforsch. 1977;47(7):627-33.
Due to the exfoliative cytology of the nipple discharge, intracanalicular proliferations within the millimeter range can be detected. Accordingly, this diagnostic method is firmly integrated in the mammary early diagnostics. Within the period reported on so far 3420 women with a pathological secretion could be examined. In 1669 cases there was a bilateral secretion. Thus, altogether 5089 mammae could be cytologically explored. Mammary cytodiagnostics was centered on the bleeding mamma, the myotheliae and galactophoritis. In addition exfoliative cytology can also yield some other diagnostic results, such as the detection of fungiproved in respective cultures. Galactography which was performed in 1053 cases, may be considered to be the only diagnostic consequence resulting from a pathological cytotest. Every 6th galactogram had to be judged as being pathological, and every 5th galactogram histologically clarified revealed a malignant or premalignant proliferation. Accordingly, women manifesting a pathological secretion should be regarded as risk-patients.
由于乳头溢液的脱落细胞学检查,毫米范围内的管内增殖能够被检测到。因此,这种诊断方法已牢固地融入乳腺早期诊断之中。在迄今所报道的时间段内,对3420例有病理分泌物的女性进行了检查。其中1669例为双侧溢液。这样,总共对5089个乳房进行了细胞学检查。乳腺细胞诊断主要针对出血性乳房、肌上皮和输乳管炎。此外,脱落细胞学检查还能得出一些其他诊断结果,比如在相应培养物中证实有真菌。在1053例中进行了乳管造影,这可被视为病理细胞检查产生的唯一诊断结果。每6次乳管造影中有1次被判定为病理结果,每5次经组织学明确的乳管造影显示有恶性或癌前增殖。因此,有病理分泌物的女性应被视为高危患者。