Hart B L
Science. 1968 Jun 7;160(3832):1135-6. doi: 10.1126/science.160.3832.1135.
Most male rats castrated 4 days after birth and given exogenous testosterone in adulthood were sexually motivated but incapable of completing the mating sequence with an ejaculatory response. When tested for sexual reflexes after spinal transection, these animals displayed impairment of genital responses. Similarly treated 12-day castrates exhibited a complete mating sequence and had normal sexual reflexes. Thus neonatal testicular androgen appears to have an organizational influence at the spinal level on neural tissue mediating sexual reflexes.
大多数在出生后4天被阉割并在成年后给予外源性睾酮的雄性大鼠有性动机，但无法通过射精反应完成交配过程。当在脊髓横断后测试性反射时，这些动物表现出生殖器反应受损。同样处理的12日龄去势大鼠表现出完整的交配过程且有正常的性反射。因此，新生儿期睾丸雄激素似乎在脊髓水平对介导性反射的神经组织具有组织性影响。
