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新生期刺激、母性行为与BALB/c小鼠的加速成熟

Neonatal stimulation, maternal behavior, and accelerated maturation in BALB/c mice.

作者信息

Cross M S, Labarba R C

出版信息

Dev Psychobiol. 1978 Jan;11(1):83-92. doi: 10.1002/dev.420110112.

DOI:10.1002/dev.420110112
PMID:564798
Abstract

An experiment was conducted to examine the effects of neonatal handling and hypothermia on infant physical maturation and growth and on maternal behavior in BALB/c mice. Stringent methodological and statistical controls were employed for experimenter bias and litter effects. No evidence appeared to support claims that neonatal stimulation leads to accelerated physical maturation. Alterations in maternal behavior patterns were found only immediately following hypothermia of pups. Maternal behavior did not correlate highly with offspring maturational rates, but maternal weight and age and pup birth weight were highly predictive of infant physical maturation.

摘要

进行了一项实验,以研究新生小鼠处理和低温对BALB/c小鼠幼崽身体成熟、生长以及母性行为的影响。实验采用了严格的方法学和统计学控制,以消除实验者偏差和窝效应。没有证据支持新生儿刺激会导致身体成熟加速的说法。仅在幼崽体温过低后立即发现母性行为模式有改变。母性行为与后代成熟率的相关性不高,但母鼠体重、年龄和幼崽出生体重对幼崽身体成熟具有高度预测性。

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