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胃空肠吻合术加重的麸质过敏性肠病中绒毛结构的恢复。

Recovery of villous architecture in gluten enteropathy exacerbated by gastro-jejunal anastomosis.

作者信息

Weir D G

出版信息

Postgrad Med J. 1968 Mar;44(509):234-7. doi: 10.1136/pgmj.44.509.234.

DOI:10.1136/pgmj.44.509.234
PMID:5648668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2466371/
Abstract

Two patients are described whose clinical condition deteriorated following gastric surgery for peptic ulceration. Both were demonstrated to be suffering from gluten enteropathy with generalized malabsorption which included lactose. Following treatment with a gluten-free diet over a 2-year period the jejunal mucosa showed a marked improvement of villous architecture associated with a return of lactose absorption to normal in one patient. This supports the view that following a gastro-jejunal anastomosis the gastric secretion is not itself injurious to the jejunal mucosal structure.

摘要

本文描述了两名患者,他们因消化性溃疡接受胃手术后临床状况恶化。两人均被证实患有麸质肠病并伴有包括乳糖在内的全身性吸收不良。在接受无麸质饮食治疗两年后,空肠黏膜显示绒毛结构明显改善,其中一名患者的乳糖吸收恢复正常。这支持了以下观点:胃空肠吻合术后,胃分泌本身不会损害空肠黏膜结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198a/2466371/38739408cdad/postmedj00375-0039-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198a/2466371/a50b0a442ded/postmedj00375-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198a/2466371/38739408cdad/postmedj00375-0039-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198a/2466371/a50b0a442ded/postmedj00375-0039-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/198a/2466371/38739408cdad/postmedj00375-0039-b.jpg

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引用本文的文献

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本文引用的文献

1
Alimentary histology in the malabsorption syndrome following partial gastrectomy.胃部分切除术后吸收不良综合征的消化管组织学
Lancet. 1959 Sep 19;2(7099):379-82. doi: 10.1016/s0140-6736(59)91641-1.
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The absorption and utilization of vitamin B12.
Am J Clin Nutr. 1955 Jan-Feb;3(1):45-51. doi: 10.1093/ajcn/3.1.45.
3
LACTASE DEFICIENCY IN ADULTS. A CAUSE OF "FUNCTIONAL" DIARRHOEA.成人乳糖酶缺乏症:“功能性”腹泻的一个病因
Lancet. 1965 Apr 3;1(7388):717-20. doi: 10.1016/s0140-6736(65)92081-7.
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FOLIC ACID DEFICIENCY IN PATIENTS AFTER GASTRIC RESECTION.胃切除术后患者的叶酸缺乏
Q J Med. 1965 Jan;34:1-14.
5
LACTASE DEFICIENCY IN THE ADULT. A COMMON OCCURRENCE.成人乳糖酶缺乏症:一种常见情况。
Lancet. 1965 Jan 2;1(7375):14-8. doi: 10.1016/s0140-6736(65)90922-0.
6
COMPARISON OF JEJUNAL MUCOSA IN POST-GASTRECTOMY STATES, IDIOPATHIC STEATORRHOEA, AND CONTROLS USING THE DISSECTING MICROSCOPE AND CONVENTIONAL HISTOLOGICAL METHODS.使用解剖显微镜和传统组织学方法对胃切除术后状态、特发性脂肪泻及对照组的空肠黏膜进行比较
Gut. 1964 Dec;5(6):553-62. doi: 10.1136/gut.5.6.553.
7
STUDIES OF CELIAC SPRUE. IV. THE RESPONSE OF THE WHOLE LENGTH OF THE SMALL BOWEL TO A GLUTEN-FREE DIET.乳糜泻研究。IV. 小肠全长对无麸质饮食的反应。
Gastroenterology. 1964 Dec;47:573-89.
8
A CLINICAL EVALUATION OF THE D-XYLOSE TOLERANCE TEST.D-木糖耐受性试验的临床评估
Ann Intern Med. 1964 Sep;61:411-22. doi: 10.7326/0003-4819-61-3-411.
9
ASPECTS OF NUTRITION AFTER VAGOTOMY AND GASTROJEJUNOSTOMY.迷走神经切断术与胃空肠吻合术后的营养问题
Br Med J. 1964 Feb 22;1(5381):465-9. doi: 10.1136/bmj.1.5381.465.
10
Anaemia following gastric operations for peptic ulceration in Dublin. II. Deficiency of iron and vitamin B12.
Ir J Med Sci. 1963 Apr;448:151-8. doi: 10.1007/BF02947194.