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[Intraportal and intravenous administration of fat emulsions. Comparison of liver morphology in animal experiments].

作者信息

Statz A, Heinisch H M

出版信息

Infusionsther Klin Ernahr. 1978 Feb;5(1):54-6.

PMID:564875
Abstract

In short infusion series run over 5 days, a fat emulsion on the basis of soya oil with egg lecithin used as emulsifier has been infused to rabbits by the intravenous and intraportal routes in a dosage of 2 and 4 g/kg bodyweight/day. By a light-microscopic analysis of the liver morphology after one and three weeks, mainly a fatty degeneration of the Kupffer's cells of the liver was found. It was considerably less conspicuous after endo-portal supply than after peripheric-intravenous supply--findings which became more obvious with the higher dose.

摘要

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