伤口愈合过程中上皮细胞和成肌纤维细胞中的细胞质细丝和间隙连接
Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing.
作者信息
Gabbiani G, Chaponnier C, Hüttner I
出版信息
J Cell Biol. 1978 Mar;76(3):561-8. doi: 10.1083/jcb.76.3.561.
Abstract
During the healing of an experimental skin wound, epidermal cells and granulation tissue fibroblasts (myofibroblasts) develop an extensive cytoplasmic contactile apparatus. Concurrently, the proportion of epidermal cell surface occupied by gap junctions increases when compared to normal skin, and newly formed gap junctions appear between myofibroblasts; this suggests that epidermal cell migration and granulation tissue contraction are synchronized phenomena.
摘要
在实验性皮肤伤口愈合过程中，表皮细胞和肉芽组织成纤维细胞（肌成纤维细胞）会形成广泛的细胞质收缩装置。同时，与正常皮肤相比，间隙连接所占据的表皮细胞表面比例增加，并且新形成的间隙连接出现在肌成纤维细胞之间；这表明表皮细胞迁移和肉芽组织收缩是同步现象。
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