关于青蛙皮肤黑素细胞跨膜电位及黑色素颗粒移动的笔记
A note on transmembrane potential in dermal melanophores of the frog and movement of melanin granules.
作者信息
Martin A R, Snell R S
出版信息
J Physiol. 1968 Apr;195(3):755-9. doi: 10.1113/jphysiol.1968.sp008487.
Abstract
- Transmembrane potentials were measured and distribution of melanin granules observed in dermal melanophores of the isolated frog's web.2. In normal Ringer solution, melanin granules were aggregated in the cell bodies and the transmembrane potentials were usually in the range 70-90 mV.3. Addition of alpha-melanocyte stimulating hormone (alpha-MSH) to the bathing solution resulted in dispersion of the melanin granules into the processes of the cells, without any accompanying change in membrane potentials. Altering the membrane potentials by changing the external K(+) concentration had no effect on melanin migration.4. It is concluded that migration of melanin granules in these cells is unrelated to cell membrane polarization.
摘要
测量了分离出的青蛙蹼真皮黑素细胞中的跨膜电位，并观察了黑色素颗粒的分布。
在正常任氏液中，黑色素颗粒聚集在细胞体中，跨膜电位通常在70 - 90 mV范围内。
向浴液中添加α - 黑素细胞刺激素（α - MSH）导致黑色素颗粒分散到细胞突起中，而膜电位没有任何伴随变化。通过改变细胞外钾离子浓度来改变膜电位对黑色素迁移没有影响。
得出结论：这些细胞中黑色素颗粒的迁移与细胞膜极化无关。
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