粗糙革兰氏阴性菌对血清杀菌作用的敏感性。
Sensitivity of rough gram-negative bacteria to the bactericidal action of serum.
作者信息
Rowley D
出版信息
J Bacteriol. 1968 May;95(5):1647-50. doi: 10.1128/jb.95.5.1647-1650.1968.
Abstract
Three Salmonella minnesota rough mutants were found to be more sensitive to the bactericidal action of antibody and complement than was the parent smooth strain. The antibodies involved were shown to be against components which are all present in the smooth parent strain and are not identical with the lipopolysaccharides isolated by the phenol-water extraction procedure. The lipopolysaccharide of the smooth strain was shown to confer resistance by blocking access of antibody to the sensitive antigens.
摘要
已发现三株明尼苏达沙门氏菌粗糙型突变体比其亲本光滑型菌株对抗体和补体的杀菌作用更敏感。所涉及的抗体显示针对的成分在光滑型亲本菌株中均存在，且与通过酚 - 水提取法分离的脂多糖不同。光滑型菌株的脂多糖通过阻止抗体接近敏感抗原来赋予抗性。
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