继发于突变血红蛋白（肯普西血红蛋白）氧亲和力增加的红细胞增多症 - Suppr

Suppr

超能文献

Erythrocytosis secondary to increased oxygen affinity of a mutant hemoglobin, hemoglobin Kempsey.

作者信息

Reed C S, Hampson R, Gordon S, Jones R T, Novy M J, Brimhall B, Edwards M J, Koler R D

出版信息

Blood. 1968 May;31(5):623-32.

PMID:5651043

Abstract

摘要

相似文献

Erythrocytosis secondary to increased oxygen affinity of a mutant hemoglobin, hemoglobin Kempsey.继发于突变血红蛋白（肯普西血红蛋白）氧亲和力增加的红细胞增多症

Blood. 1968 May;31(5):623-32.

Erythrocytosis associated with hemoglobin Rainier: oxygen equilibria and marrow regulation.与雷尼尔血红蛋白相关的红细胞增多症：氧平衡与骨髓调节

J Clin Invest. 1969 Aug;48(8):1376-86. doi: 10.1172/JCI106103.

Familial erythrocytosis. A description of three families, one with hemoglobin Ypsilanti.家族性红细胞增多症。对三个家族的描述，其中一个家族携带伊普西兰蒂血红蛋白。

Ann Intern Med. 1968 Oct;69(4):769-76. doi: 10.7326/0003-4819-69-4-769.

Recessive familial erythrocytosis: aspects of marrow regulation in two families.

Blood. 1973 May;41(5):641-52.

[Polycythemia resulting from abnormal hemoglobin with increased affinity for oxygen. Two cases (author's transl)].因血红蛋白异常对氧亲和力增加所致的红细胞增多症。两例（作者译）

Nouv Presse Med. 1980 Jan 26;9(5):285-9.

The JAK2 V617F mutation is absent in patients with erythrocytosis due to high oxygen affinity hemoglobin variants.由于高氧亲和力血红蛋白变异体导致的红细胞增多症患者不存在JAK2 V617F突变。

Hemoglobin. 2006;30(4):487-9. doi: 10.1080/03630260600868147.

Hemoglobins with high oxygen affinity leading to erythrocytosis. New variants and new concepts.具有高氧亲和力导致红细胞增多症的血红蛋白。新变体和新概念。

Hemoglobin. 2005;29(2):91-106.

Homozygous hemoglobin Abruzzo in a North American child.一名北美儿童中的纯合子血红蛋白阿布鲁佐

J Pediatr Hematol Oncol. 2005 Nov;27(11):618-20. doi: 10.1097/01.mph.0000188114.50200.b3.

Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.圣纳泽尔血红蛋白（β103[G5]苯丙氨酸→异亮氨酸）：一种因氧亲和力增加的血红蛋白变异导致的红细胞增多症的新病例。

Am J Hematol. 1993 Sep;44(1):16-21. doi: 10.1002/ajh.2830440105.

Hb Tsurumai [beta 82(EF6)Lys-->Gln]: a new Hb variant with high oxygen affinity and erythrocytosis.鹤舞血红蛋白[β82(EF6)赖氨酸→谷氨酰胺]：一种具有高氧亲和力和红细胞增多症的新型血红蛋白变异体。

Hemoglobin. 1996 May;20(2):141-6. doi: 10.3109/03630269609027920.

引用本文的文献

Hemoglobin Variants as Targets for Stabilizing Drugs.作为稳定药物靶点的血红蛋白变体

Molecules. 2025 Jan 17;30(2):385. doi: 10.3390/molecules30020385.

Hypoxia-inducible factors link iron homeostasis and erythropoiesis.缺氧诱导因子将铁稳态和红细胞生成联系起来。

Gastroenterology. 2014 Mar;146(3):630-42. doi: 10.1053/j.gastro.2013.12.031. Epub 2013 Dec 31.

Collective dynamics underlying allosteric transitions in hemoglobin.血红蛋白变构转变的集体动力学。

PLoS Comput Biol. 2013;9(9):e1003232. doi: 10.1371/journal.pcbi.1003232. Epub 2013 Sep 19.

Hemoglobin variants: biochemical properties and clinical correlates.血红蛋白变体：生化特性与临床关联。

Cold Spring Harb Perspect Med. 2013 Mar 1;3(3):a011858. doi: 10.1101/cshperspect.a011858.

Familial secondary erythrocytosis due to increased oxygen affinity is caused by destabilization of the T state of hemoglobin Brigham (α₂β₂(Pro100Leu)).家族性继发性红细胞增多症由于血红蛋白 Brigham 的 T 态不稳定（α₂β₂(Pro100Leu)）导致氧亲和力增加所致。

Protein Sci. 2012 Oct;21(10):1444-55. doi: 10.1002/pro.2130. Epub 2012 Aug 21.

An investigation of the distal histidyl hydrogen bonds in oxyhemoglobin: effects of temperature, pH, and inositol hexaphosphate.氧合血红蛋白中远端组氨酸氢键的研究：温度、pH 值和肌醇六磷酸的影响。

Biochemistry. 2010 Dec 21;49(50):10606-15. doi: 10.1021/bi100927p. Epub 2010 Nov 29.

Properties of a recombinant human hemoglobin with aspartic acid 99(beta), an important intersubunit contact site, substituted by lysine.一种重组人血红蛋白的特性，其99位（β链）天冬氨酸（一个重要的亚基间接触位点）被赖氨酸取代。

Protein Sci. 1994 Aug;3(8):1213-23. doi: 10.1002/pro.5560030807.

Restoring allosterism with compensatory mutations in hemoglobin.通过血红蛋白中的补偿性突变恢复变构作用。

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11547-51. doi: 10.1073/pnas.91.24.11547.

A proton nuclear magnetic resonance investigation of proximal histidyl residues in human normal and abnormal hemoglobins. A probe for the heme pocket.对人正常和异常血红蛋白中近端组氨酸残基的质子核磁共振研究。血红素口袋的一种探针。

Biophys J. 1982 Jul;39(1):33-40. doi: 10.1016/S0006-3495(82)84487-1.

Polycythemia: diagnosis, pathophysiology and therapy. I.真性红细胞增多症：诊断、病理生理学与治疗。I.

Can Med Assoc J. 1969 Feb 8;100(6):271-7.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验