人红细胞对氯化铵通透性的动力学分析
Kinetic analysis of the permeability of human erythrocytes to NH4C1.
作者信息
Hunter F R
出版信息
J Gen Physiol. 1968 Apr;51(4):579-87. doi: 10.1085/jgp.51.4.579.
A densimeter technique was used to make a kinetic analysis of the rate of swelling of human erythrocytes suspended in 1% NaCl following successive additions of NH(4)Cl. Two series of experiments were performed, one in the absence of and the other in the presence of 6 x 10(-4)M NaHCO(3). An analysis of the data using Widdas's equations gave a family of curves in each instance. When LeFevre's equation was used with a value of ø = 1.3 isotones, a straight line was obtained with both series of data. It is concluded that this system shows carrier kinetics.
采用密度计技术对连续添加氯化铵后悬浮于1%氯化钠溶液中的人红细胞肿胀速率进行动力学分析。进行了两个系列的实验，一个系列在无6×10⁻⁴M碳酸氢钠的情况下进行，另一个系列在有6×10⁻⁴M碳酸氢钠的情况下进行。使用维达斯方程对数据进行分析，在每种情况下都得到了一组曲线。当使用勒费夫尔方程且ø值为1.3等渗时，两个系列的数据均得到一条直线。得出的结论是，该系统显示出载体动力学。
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