Wildt D E, Seager S W
Horm Res. 1978;9(3):144-50. doi: 10.1159/000178907.
Laparoscopy was utilized to determine the ovulatory response of the domestic cat to various dosages of human chorionic gonadotropin (HCG) administered intramuscularly at one or two time periods during estrus. A linear HCG dose-ovulatory response was observed in queens receiving 0--500 IU HCG as a single injection on day 1 or as injections given on days 1 and 2 of estrus. Animals treated with 500 IU HCG on day 1 or days 1 and 2 of estrus produced the maximum percent ovulation rates based on pre- and post-HCG ovarian morphology observation by laparoscopy (100.0, 95.9%, respectively). A single injection of 500 IU HCG produced a significant increase (p less than 0.05) in mean percent ovulation rate in comparison to the 0, 50 and 100 IU HCG single injections. Administration of 500 and 250 IU HCG for 2 days of estrus resulted in a greater percent ovulation rate than the 2-day injection of 50 IU (p less than 0.05). These results indicate that the proportion of mature follicles ovulating in an induced ovulator, such as the cat, is an increasing function of graded dosages of exogenous hormone.
利用腹腔镜检查来确定家猫对在发情期的一个或两个时间段肌肉注射不同剂量人绒毛膜促性腺激素（HCG）的排卵反应。在发情期第1天单次注射0 - 500国际单位HCG或在发情期第1天和第2天注射的母猫中，观察到了线性的HCG剂量 - 排卵反应。根据腹腔镜检查对注射HCG前后卵巢形态的观察，在发情期第1天或第1天和第2天接受500国际单位HCG治疗的动物排卵率百分比最高（分别为100.0%、95.9%）。与0、50和100国际单位HCG单次注射相比，单次注射500国际单位HCG使平均排卵率百分比显著增加（p < 0.05）。在发情期2天内注射500和250国际单位HCG导致的排卵率百分比高于2天注射50国际单位的情况（p < 0.05）。这些结果表明，在诱导排卵动物（如猫）中，成熟卵泡排卵的比例是外源激素分级剂量的递增函数。
