心脏内保存的同种异体心包和自体心包的转归。

Clarke C P, Barratt-Boyes B G, Sims F H

Thorax. 1968 Mar;23(2):111-20. doi: 10.1136/thx.23.2.111.

Animal experiments were performed to assess the usefulness of preserved homograft pericardium for intracardiac surgery, with particular reference to the problem of homograft mitral valve papillary muscle fixation. The fate of fresh autogenous pericardium was also studied. Both homograft and autogenous pericardium were destroyed and replaced by fibrous tissue. This reaction was faster when the pericardium was in direct contact with the blood stream and slower when it was buried within the myocardium. As homograft pericardium provided a more intense fibrous reaction than autogenous pericardium, it was considered to be very suitable for papillary muscle fixation and less suitable for other intracardiac procedures. The technique used for attaching the papillary muscle of a homograft mitral valve is briefly described.

进行动物实验以评估保存的同种异体心包在心脏手术中的效用，尤其涉及同种异体二尖瓣乳头肌固定的问题。还研究了新鲜自体心包的转归。同种异体心包和自体心包均被破坏并被纤维组织替代。当心包直接与血流接触时，这种反应更快，而当它埋于心肌内时则较慢。由于同种异体心包比自体心包引发更强烈的纤维反应，因此它被认为非常适合乳头肌固定，而不太适合其他心脏内手术。简要描述了用于连接同种异体二尖瓣乳头肌的技术。