Avila R
Thorax. 1968 Mar;23(2):144-52. doi: 10.1136/thx.23.2.144.
The various phases of pulmonary aspergilloma, as described by Pimentel, are discussed and the results of an investigation of possible cases of this disease in patients whose condition made its presence likely are presented. A systematic search for Aspergillus precipitins in the sera of 136 patients was undertaken with antigens. By this method two cases of pulmonary aspergilloma were diagnosed and later confirmed at operation. In a third patient the immunological diagnosis was negative but an aspergilloma was found at operation. This finding is discussed and a possible hypothesis is suggested. A pathological study of the surgical specimens is desirable to explain the false-negative Aspergillus precipitin reactions reported by various authors.
本文讨论了皮门特尔所描述的肺曲菌球的各个阶段，并展示了对病情可能存在该病的患者进行的相关调查结果。我们用抗原对136名患者的血清进行了系统性曲霉菌沉淀素检测。通过这种方法，诊断出两例肺曲菌球，随后手术确诊。第三例患者免疫诊断为阴性，但手术中发现了曲菌球。本文对此发现进行了讨论并提出了一个可能的假设。需要对手术标本进行病理研究，以解释不同作者报道的曲霉菌沉淀素反应假阴性情况。
