Blackwell R W, Liu C S, Yang H J, Wang C C, Huang J T
Science. 1968 Jul 26;161(3839):381-2. doi: 10.1126/science.161.3839.381.
An electrophoretically slow hemoglobin variant, in which the structural change involves the replacement of a glutamyl residue by alanyl at position beta-22, was reported in two groups of North American Indians: hemoglobin-G Coushatta, in Alabama-Coushatta Indians in Texas; and hemoglobin-G Saskatoon, in descendants of Santee Indians living in Canada. Hemoglobin-G Hsin-Chu, found in Taiwan in a Chinese from the northern Chinese province of Liaoning, is now shown to have the same structural anomaly.
一种电泳迁移缓慢的血红蛋白变异体,其结构变化涉及β-22位的谷氨酰残基被丙氨酰残基取代,在两组北美印第安人中被报道:血红蛋白-G库沙塔,在得克萨斯州的阿拉巴马-库沙塔印第安人中;以及血红蛋白-G萨斯卡通,在居住在加拿大的桑蒂印第安人的后裔中。在台湾一名来自中国北方辽宁省的中国人中发现的血红蛋白-G新竹,现在显示具有相同的结构异常。