Krachmer J H, Anderson R L, Binder P S, Waring G O, Rowsey J J, Meek E S
Am J Ophthalmol. 1978 May;85(5 Pt 1):666-70. doi: 10.1016/s0002-9394(14)77102-8.
We studied four cases of Helminthosporium corneal ulcers from four different institutions. One case occurred in an immune-deficient infant, another in a patient three months after removal of a foreign body; the third case occurred in a patient with a corneal dystrophy who was wearing soft contact lenses and using topical corticosteroids; and the fourth occurred in a patient with a history of multiple foreign bodies. Antifungal sensitivities were performed in three cases and showed relatively good sensitivity to available antifungal medications; even though all four patients improved, there was poor correlation between in vitro sensitivities and clinical response.
我们研究了来自四个不同机构的4例弯孢霉性角膜溃疡病例。1例发生在免疫缺陷婴儿中，另1例发生在异物取出3个月后的患者中；第3例发生在患有角膜营养不良且佩戴软性隐形眼镜并使用局部皮质类固醇的患者中；第4例发生在有多次异物史的患者中。对3例进行了抗真菌药敏试验，结果显示对现有抗真菌药物有相对较好的敏感性；尽管所有4例患者均有改善，但体外药敏试验结果与临床反应之间的相关性较差。
