Molecular defects in haemophilia A and von Willebrand's disease.
作者信息
Gralnick H R, Coller B S
出版信息
Lancet. 1976 Apr 17;1(7964):837-8. doi: 10.1016/s0140-6736(76)90485-2.
PMID:56653
Abstract
A model is proposed for the synthesis of the factor VII/von Willebrand factor protein. The defect(s) in von Willebrand's disease are related to abnormalities of the protein subunit and/or its carbohydrate content, while in haemophilia the abnormality is related to a deficiency or abnormality of the X-dependent enzyme or protein which is involved in the generation of procoagulant activity of the factor VII/von Willebrand factor multimer.
摘要
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引用本文的文献
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