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The effect of sodium depletion of the renal response to water-loading in dogs.钠缺乏对犬肾对水负荷反应的影响。
J Physiol. 1968 Aug;197(3):617-30. doi: 10.1113/jphysiol.1968.sp008577.

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The excretion of administered sodium chloride by the conscious dog, and the effect of occlusion of the carotid arteries.清醒犬对注入氯化钠的排泄以及颈动脉闭塞的影响。
Q J Exp Physiol Cogn Med Sci. 1955 Jul;40(3):237-57. doi: 10.1113/expphysiol.1955.sp001120.
2
THE MECHANISM OF SODIUM DURESIS AFTER SALINE INFUSION IN THE DOG.狗静脉输注生理盐水后钠利尿的机制
J Clin Invest. 1963 Aug;42(8):1261-76. doi: 10.1172/JCI104811.
3
Renal response to measured blood volume expansion in differently hydrated dogs.不同水合状态犬对测量的血容量扩张的肾脏反应。
Am J Physiol. 1962 Aug;203:344-52. doi: 10.1152/ajplegacy.1962.203.2.344.
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Mechanisms of hyponatremia in chronic congestive heart failure.
Ann Intern Med. 1961 Sep;55:368-83. doi: 10.7326/0003-4819-55-3-368.
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Mechanisms of the renal response to plasma volume expansion.肾脏对血容量扩张反应的机制。
Can J Biochem Physiol. 1959 Jan;37(1):91-102.
6
The effect of intravenously infused saline on the renal clearances of inulin and para-aminohippurate in dogs.
Q J Exp Physiol Cogn Med Sci. 1967 Apr;52(2):145-9. doi: 10.1113/expphysiol.1967.sp001896.

输注血浆和生理盐水对缺钠犬肾脏对水负荷反应的影响。

The effect of infusions of plasma and of saline on the renal response to water-loading in sodium-depleted dogs.

作者信息

Coxon R V, Ramsay D J

出版信息

J Physiol. 1968 Aug;197(3):631-8. doi: 10.1113/jphysiol.1968.sp008578.

DOI:10.1113/jphysiol.1968.sp008578
PMID:5666178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1351752/
Abstract
  1. Infusion of 150 ml. of plasma to dogs acutely depleted of sodium chloride by peritoneal dialysis with glucose (5 g/100 ml.) does not restore their ability to respond by diuresis when given 2.5% body weight of water by mouth.2. Infusion of 300 ml. of saline (0.73g NaCl/100 ml.) to these animals results in a brisk increase in urinary flow.3. Infusion of 100 ml. of saline (0.73g NaCl/100 ml.) to sodium-depleted dogs restores their ability to respond to a water-load of 2.5% of body weight by diuresis.4. The results are discussed and a tentative explanation put forward.
摘要

  1. 给通过用葡萄糖（5克/100毫升）进行腹膜透析而急性缺氯化钠的狗输注150毫升血浆，当经口给予相当于体重2.5%的水时，它们不会恢复通过利尿做出反应的能力。

  2. 给这些动物输注300毫升生理盐水（0.73克氯化钠/100毫升）会导致尿流量迅速增加。

  3. 给缺钠的狗输注100毫升生理盐水（0.73克氯化钠/100毫升）可恢复它们对相当于体重2.5%的水负荷做出利尿反应的能力。

  4. 对结果进行了讨论并提出了一个初步解释。