Goldwasser E
Biochem J. 1968 Jul;108(3):413-5. doi: 10.1042/bj1080413.
The activities of the eight citric acid-cycle enzymes of rat bone-marrow cells were determined along with several other mitochondrial and non-mitochondrial enzymes. Four of the citric acid-cycle enzymes (aconitase, succinyl-CoA thiokinase, alpha-oxoglutarate dehydrogenase and succinate dehydrogenase) have closely similar low activities; two [isocitrate dehydrogenase (NAD) and citrate synthase] have intermediate activities; the remaining two (malate dehydrogenase and fumarase) have high activities. The other enzymes surveyed also exhibited a spread of three orders of magnitude, the mitochondrial enzymes showing no less variation than the others.
测定了大鼠骨髓细胞中八种柠檬酸循环酶的活性，以及其他几种线粒体和非线粒体酶的活性。四种柠檬酸循环酶（乌头酸酶、琥珀酰辅酶A硫激酶、α-酮戊二酸脱氢酶和琥珀酸脱氢酶）具有非常相似的低活性；两种酶[异柠檬酸脱氢酶（NAD）和柠檬酸合酶]具有中等活性；其余两种酶（苹果酸脱氢酶和延胡索酸酶）具有高活性。所检测的其他酶也呈现出三个数量级的分布范围，线粒体酶的变化程度与其他酶相比毫不逊色。
