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黏菌盘基网柄菌分化过程中糖脂的生物合成。

The biosynthesis of glycolipids during the differentiation of the slime mold Dictyostelium discoideum.

作者信息

Rössler H, Peuckert W, Risse H J

出版信息

Mol Cell Biochem. 1978 Jun 15;20(1):3-15. doi: 10.1007/BF00229450.

DOI:10.1007/BF00229450
PMID:566848
Abstract

In the slime mold Dictyostelium discoideum polysioprenylphosphomannosides are substrates for membrane bound mannosyltransferases; the isolated and purified isoprenyl derivatives transfer mannose to protein in vitro in presence of membrane fractions. The biosynthesis of the mannolipids as well as the biosynthesis of a glucose containing cerebroside, which becomes synthesized in an early stage of the cell development proceeds under control of the cell differentiation. The isolation procedure and the properties of the glycolipids are described, and their functions for the cellular development are discussed.

摘要

在黏菌盘基网柄菌中,多异戊二烯基磷酸甘露糖苷是膜结合甘露糖基转移酶的底物;分离纯化的异戊二烯基衍生物在膜组分存在的情况下,能在体外将甘露糖转移到蛋白质上。甘露糖脂的生物合成以及一种含葡萄糖的脑苷脂的生物合成(其在细胞发育的早期阶段合成)是在细胞分化的控制下进行的。本文描述了糖脂的分离方法及其性质,并讨论了它们在细胞发育中的作用。

相似文献

1
The biosynthesis of glycolipids during the differentiation of the slime mold Dictyostelium discoideum.黏菌盘基网柄菌分化过程中糖脂的生物合成。
Mol Cell Biochem. 1978 Jun 15;20(1):3-15. doi: 10.1007/BF00229450.
2
Synthesis of a mannosyl phosphoryl polyprenol by the cellular slime mold Dictyostelium discoideum.细胞黏菌盘基网柄菌合成甘露糖基磷酸化聚异戊二烯醇。
Biochim Biophys Acta. 1977 Jul 21;498(1):439-41. doi: 10.1016/0304-4165(77)90282-3.
3
Synthesis and translation of messenger RNA during differentiation of the cellular slime mold Dictyostelium discoideum.细胞黏菌盘基网柄菌分化过程中信使核糖核酸的合成与翻译
Symp Soc Dev Biol. 1976(34):75-103.
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Cyclic AMP levels and turnover during development of the cellular slime mold Dictyostelium discoideum.细胞黏菌盘基网柄菌发育过程中的环磷酸腺苷水平与周转
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Precursors of ribosomal RNA in the cellular slime mold Dictyostelium discoideum. Isolation and characterization.细胞黏菌盘基网柄菌中核糖体RNA的前体。分离与特性鉴定。
J Biol Chem. 1977 Jun 10;252(11):3952-60.
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The synthesis of messenger RNA in the cellular slime mold Dictyosteilum discoideum.细胞黏菌盘基网柄菌中信使核糖核酸的合成。
Brookhaven Symp Biol. 1975 Jul(26):307-19.
7
Fatty acid compositions of lipid fractions from vegetative cells and mature sorocarps of the cellular slime mold Dictyostelium discoideum.细胞黏菌盘基网柄菌营养细胞和成熟子实体脂质组分的脂肪酸组成。
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Primer dependency of glycogen synthetase during differentiation in Dictyostelium discoideum.
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Calcium control of actin-activated myosin adenosine triphosphatase from Dictyostelium discoideum.盘基网柄菌肌动蛋白激活的肌球蛋白三磷酸腺苷酶的钙调控
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Incorporation of glucose into lipid-linked saccharides in aorta and its inhibition by amphomycin.葡萄糖在主动脉中掺入脂质连接糖及其被两性霉素抑制的情况。
Arch Biochem Biophys. 1979 Nov;198(1):304-13. doi: 10.1016/0003-9861(79)90423-5.

引用本文的文献

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Monoclonal antibodies against contact sites A of Dictyostelium discoideum: detection of modifications of the glycoprotein in tunicamycin-treated cells.针对盘基网柄菌接触位点 A 的单克隆抗体:衣霉素处理细胞中糖蛋白修饰的检测。
EMBO J. 1982;1(8):1011-6. doi: 10.1002/j.1460-2075.1982.tb01286.x.
2
The dependence of glycosyltransferases in Dictyostelium discoideum on the structure of polyisoprenols.盘基网柄菌中糖基转移酶对聚异戊二烯醇结构的依赖性。
Mol Cell Biochem. 1981 Jan 28;34(2):65-72. doi: 10.1007/BF02354860.
3
Plasma membrane proteins in Dictyostelium.

本文引用的文献

1
[Differences in the pattern of macromolecules between vegetative and aggregation Competent Cells in Dictyostelium discoideum].[盘基网柄菌营养细胞和聚集感受态细胞之间大分子模式的差异]
Wilhelm Roux Arch Entwickl Mech Org. 1969 Sep;162(3):268-285. doi: 10.1007/BF00576933.
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Detection of sugars on paper chromatograms.纸色谱上糖的检测
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3
A plant mannosyl-lipid acting in reversible transfer of mannose.一种参与甘露糖可逆转移的植物甘露糖脂。
盘基网柄菌中的质膜蛋白。
Mol Cell Biochem. 1983;50(1):75-95. doi: 10.1007/BF00225281.
4
A differentiation-dependent polyisoprenol kinase in Dictyostelium discoideum.盘基网柄菌中一种依赖分化的聚异戊二烯醇激酶。
Mol Cell Biochem. 1982 Oct 29;48(3):183-9. doi: 10.1007/BF00421227.
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Modifications of lysosomal enzymes in Dictyostelium discoideum.盘基网柄菌中溶酶体酶的修饰
Mol Cell Biochem. 1986 Nov-Dec;72(1-2):47-65. doi: 10.1007/BF00230635.
6
Products of endogenous N-acetylglucosaminyltransferase activity of Dictyostelium discoideum during growth and early development.盘基网柄菌生长和早期发育过程中内源性N-乙酰葡糖胺基转移酶活性的产物
J Bacteriol. 1979 Oct;140(1):188-96. doi: 10.1128/jb.140.1.188-196.1979.
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A lipid intermediate in mannan biosynthesis in yeast.酵母中甘露聚糖生物合成的一种脂质中间体。
Biochem Biophys Res Commun. 1969 Apr 10;35(1):144-50. doi: 10.1016/0006-291x(69)90496-3.
5
Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture.细胞黏菌盘基网柄菌的黏变形体在无菌培养中的生长。
Biochem J. 1970 Sep;119(2):171-4. doi: 10.1042/bj1190171.
6
Developmental regulation of alpha-mannosidase in Dictyostelium discoideum.盘基网柄菌中α-甘露糖苷酶的发育调控
J Bacteriol. 1970 Aug;103(2):375-81. doi: 10.1128/jb.103.2.375-381.1970.
7
Dolichol monophosphate glucose: an intermediate in glucose transfer in liver.磷酸多萜醇葡萄糖:肝脏中葡萄糖转移的中间体。
Proc Natl Acad Sci U S A. 1970 May;66(1):153-9. doi: 10.1073/pnas.66.1.153.
8
Structure of a lipid intermediate in cell wall peptidoglycan synthesis: a derivative of a C55 isoprenoid alcohol.细胞壁肽聚糖合成中脂质中间体的结构:一种C55类异戊二烯醇的衍生物。
Proc Natl Acad Sci U S A. 1967 Jun;57(6):1878-84. doi: 10.1073/pnas.57.6.1878.
9
Biosynthesis of glycoproteins of the Ehrlich ascites carcinoma cell membranes.艾氏腹水癌细胞膜糖蛋白的生物合成
Proc Natl Acad Sci U S A. 1965 Jul;54(1):247-52. doi: 10.1073/pnas.54.1.247.
10
The biosynthesis of glycoproteins during the development of Dictyostelium discoideum. The transfer of D-mannose in vegetative and aggregated cells.
Eur J Biochem. 1971 Jul 29;21(2):179-90. doi: 10.1111/j.1432-1033.1971.tb01454.x.