细胞黏菌盘基网柄菌合成甘露糖基磷酸化聚异戊二烯醇。
Synthesis of a mannosyl phosphoryl polyprenol by the cellular slime mold Dictyostelium discoideum.
作者信息
Crean E V, Rossomando E F
出版信息
Biochim Biophys Acta. 1977 Jul 21;498(1):439-41. doi: 10.1016/0304-4165(77)90282-3.
PMID:560218
Abstract
A membrane fraction isolated from the cellular slime mold Dictyostelium discoideum was incubated with GDP-[14C]mannose and found to catalyze the incorporation of [14C]mannose into an endogenous acceptor to yield a product with the chemical and chromatographic properties of a polyprenol phosphate sugar derivative. These results suggest that D. discoideum can synthesize a mannosyl phosphoryl polyprenol.
摘要
从细胞黏菌盘基网柄菌中分离出的膜部分与GDP-[14C]甘露糖一起孵育，发现它能催化将[14C]甘露糖掺入内源性受体，从而产生一种具有聚异戊二烯磷酸糖衍生物化学和色谱性质的产物。这些结果表明，盘基网柄菌能够合成甘露糖基磷酸化聚异戊二烯。
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