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The synthesis of 6'-deoxyhomonucleoside-6'-phosphonic acids.

作者信息

Jones G H, Moffatt J G

出版信息

J Am Chem Soc. 1968 Sep 11;90(19):5336-8. doi: 10.1021/ja01021a086.

DOI:10.1021/ja01021a086
PMID:5670802
Abstract
摘要

相似文献

1
The synthesis of 6'-deoxyhomonucleoside-6'-phosphonic acids.6'-脱氧高核苷-6'-膦酸的合成
J Am Chem Soc. 1968 Sep 11;90(19):5336-8. doi: 10.1021/ja01021a086.
2
PHOSPHONIC ACID ANALOGS OF NUCLEOSIDE PHOSPHATES. 3. THE SYNTHESIS OF ADENOSINE-5'-METHYLENEDIPHOSPHONATE, A PHOSPHONIC ACID ANALOG OF ADENOSINE-5'-DIPHOSPHATE.核苷磷酸的膦酸类似物。3. 腺苷-5'-亚甲基二膦酸酯的合成，腺苷-5'-二磷酸的膦酸类似物。
J Org Chem. 1965 May;30:1517-20. doi: 10.1021/jo01016a043.
3
PHOSPHONIC ACID ANALOGS OF NUCLEOSIDE PHOSPHATES. II. THE SYNTHESIS OF 5'-ADENYLYL METHYLPHOSPHONATE AND 5'-ADENYLYL CHLOROMETHYLPHOSPHONATE.核苷磷酸酯的膦酸类似物。II. 5'-腺苷基甲基膦酸酯和5'-腺苷基氯甲基膦酸酯的合成。
J Org Chem. 1965 Feb;30:443-6. doi: 10.1021/jo01013a035.
4
Phosphonolipids. XXII. Synthesis of phosphonic acid analogues of L-alpha-(N-methyl)cephalins.
Can J Biochem. 1970 Feb;48(2):221-2. doi: 10.1139/o70-039.
5
Amino phosphonic acids. 3. The synthesis and properties of 2-aminoethylphosphonic and 3-aminopropylphosphonic acids.氨基膦酸。3. 2-氨基乙基膦酸和3-氨基丙基膦酸的合成与性质
J Org Chem. 1972 Dec 29;37(26):4399-401. doi: 10.1021/jo00799a608.
6
Nucleoside phosphonic acids. 3. A nucleoside phosphonic acid analog of UDP-glucose.核苷膦酸。3. UDP-葡萄糖的一种核苷膦酸类似物。
Biochim Biophys Acta. 1970 Mar 24;201(3):416-24. doi: 10.1016/0304-4165(70)90160-1.
7
Synthesis and antiviral evaluation of novel 2',2'-difluoro 5'-norcarbocyclic phosphonic acid nucleosides as antiviral agents.新型2',2'-二氟5'-去碳环膦酸核苷作为抗病毒剂的合成与抗病毒评价
Nucleosides Nucleotides Nucleic Acids. 2014;33(1):1-17. doi: 10.1080/15257770.2013.854380.
8
Phosphonic acid analogues of carbohydrate metabolites. I. Synthesis of L-and D-dihydroxypropylphosphonic acid.
Can J Biochem. 1969 Oct;47(10):955-60. doi: 10.1139/o69-150.
9
Phosphonolipids. XXI. Synthesis of phosphonic acid analogues of diether L-alpha-(N,N-dimethyl)cephalins.
Can J Biochem. 1970 Feb;48(2):184-6. doi: 10.1139/o70-029.
10
Synthesis of phosphonic analogs of enkephalins. Pentapeptides with COOH replaced by PO3H2 group.脑啡肽膦酸类似物的合成。羧基被PO3H2基团取代的五肽。
Int J Pept Protein Res. 1983 May;21(5):485-90.

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Selected Thoughts on Hydrophobicity in Drug Design.药物设计中疏水性的思考要点。
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Synthesis of 5'-methylene-phosphonate furanonucleoside prodrugs: application to D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl nucleosides.5'-亚甲基膦酸酯呋喃核苷前药的合成：在 D-2'-脱氧-2'-α-氟-2'-β-C-甲基核苷中的应用。
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Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues.尿苷 5'-磷酸类似物的合成及 P2Y₂ 受体激动剂活性。
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Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.核苷5'-膦酸酯衍生物的合成及P2Y受体活性
Bioorg Med Chem Lett. 2009 Jun 1;19(11):3002-5. doi: 10.1016/j.bmcl.2009.04.027. Epub 2009 Apr 14.
5
A new approach to the synthesis of the 5'-deoxy-5'-methylphosphonate linked thymidine oligonucleotide analogues.一种合成5'-脱氧-5'-甲基膦酸酯连接的胸腺嘧啶寡核苷酸类似物的新方法。
Nucleic Acids Res. 1995 Mar 25;23(6):893-900. doi: 10.1093/nar/23.6.893.
6
The arsonomethyl analogue of adenosine 5'-phosphate. An uncoupler of adenylate kinase.5'-磷酸腺苷的甲酰基类似物。一种腺苷酸激酶解偶联剂。
Biochem J. 1984 Aug 1;221(3):829-36. doi: 10.1042/bj2210829.
7
5'-Nucleotidase from rat heart membranes. Inhibition by adenine nucleotides and related compounds.大鼠心肌细胞膜5'-核苷酸酶。腺嘌呤核苷酸及相关化合物对其的抑制作用。
Biochem J. 1985 Mar 15;226(3):645-51. doi: 10.1042/bj2260645.
8
Polynucleotide phosphorylase forms polymers from an ADP analog in which the 5' oxygen is replaced by a methylene group.多核苷酸磷酸化酶由一种ADP类似物形成聚合物，其中5'氧被亚甲基取代。
Nucleic Acids Res. 1990 May 25;18(10):3085-6. doi: 10.1093/nar/18.10.3085.
9
Phosphonomethyl analogues of hexose phosphates.己糖磷酸酯的膦酰甲基类似物。
Biochem J. 1976 May 1;155(2):433-41. doi: 10.1042/bj1550433.
10
Dehydrogenation of the phosphonate analogue of glucose 6-phosphate by glucose 6-phosphate dehydrogenase.6-磷酸葡萄糖脱氢酶催化6-磷酸葡萄糖的膦酸酯类似物脱氢反应。
Biochem J. 1976 Apr 1;155(1):1-4. doi: 10.1042/bj1550001.