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[乳腺组织中氧张力的分布]

[Distribution of oxygen tension in breast tissues].

作者信息

Grachev I I, Galantsev V P, Kisliakova L P

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Jun;64(6):850-7.

PMID:567139
Abstract

Using a mathematical model which describes the O2, transport in the alveolar cell of the mammary gland, the distribution of pO2 levels during two stages of the secretory cycle, was calculated. At the initial stage, the typical feature of which is the increased blood flow and O2 consumption, pO2 in the secretory tissue varied from 3 to 30 torr (average 9.9 torr). At the later stage of the secretory cycle characterized by the decreased blood flow and O2 consumption, pO2 levels in the secretory tissue were within the limits of 40--60 torr (average 48.9 torr). The increase of blood flow usually observed at the initial stage of the secretory cycle seems to supply tissues with the necessary amount of O2 even if the capillarization of the alveoli is minimal.

摘要

利用一个描述乳腺腺泡细胞中氧气运输的数学模型,计算了分泌周期两个阶段的氧分压水平分布。在初始阶段,其典型特征是血流量和氧气消耗量增加,分泌组织中的氧分压在3至30托之间变化(平均9.9托)。在分泌周期的后期,其特征是血流量和氧气消耗量减少,分泌组织中的氧分压水平在40 - 60托范围内(平均48.9托)。在分泌周期初始阶段通常观察到的血流量增加似乎为组织提供了必要量的氧气,即使肺泡的毛细血管化程度最低。

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