Chronic alcohol consumption does not modify cholecystokinin blood levels estimated by bioassay in the dog.

Blood levels of cholecystokinin (CCK) were estimated by a bioassay on in vitro rabbit gallbladder in two series of dogs; 5 dogs receiving daily, for 12--18 months, 2g kg-1 ethanol through a gastric cannula and 5 control dogs which did not receive ethanol. CCK-like activity is no different in either group, neither in the fasting state nor after intraduodenal injection of oleic acid or intragastric injection of ethanol.