α-[(叔丁氨基)甲基]-4-羟基间二甲苯-α1,α3-二醇（AH.3365）：一种选择性β-肾上腺素能兴奋剂。 - Suppr

Suppr

超能文献

Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha 1,alpha 3-diol (AH.3365): a selective beta-adrenergic stimulant.

作者信息

Brittain R T, Farmer J B, Jack D, Martin L E, Simpson W T

出版信息

Nature. 1968 Aug 24;219(5156):862-3. doi: 10.1038/219862a0.

DOI:10.1038/219862a0

PMID:5673352

Abstract

摘要

相似文献

Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha 1,alpha 3-diol (AH.3365): a selective beta-adrenergic stimulant.

Nature. 1968 Aug 24;219(5156):862-3. doi: 10.1038/219862a0.

3-(Alpha-(tert-butylamino)methyl)-5-hydroxy-m-xylene-alpha, alpha'-diol, a selective bronchodilator.

J Med Chem. 1974 Oct;17(10):1112-5. doi: 10.1021/jm00256a017.

A comparison of the beta-adrenoreceptor stimulant properties of isoprenaline, with those of orciprenaline, salbutamol, soterenol and trimetoquinol on isolated atria and trachea of the guinea pig.

J Pharm Pharmacol. 1970 Jan;22(1):61-3. doi: 10.1111/j.2042-7158.1970.tb08388.x.

The bronchodilator and cardiac stimulant effects of Thll65a, salbutamol and isoproterenol.

J Pharmacol Exp Ther. 1973 Sep;186(3):472-81.

The effect of isopropylamino radical on the cardiovascular system.

Jpn Circ J. 1968 Mar;32(3):341-6. doi: 10.1253/jcj.32.341.

An examination of some -adrenoreceptor stimulants for selectivity using the isolated trachea and atria of the guinea pig.

Eur J Pharmacol. 1972 Sep;19(3):371-9. doi: 10.1016/0014-2999(72)90104-5.

A comparison of the beta-adrenoceptor stimulant properties of salbutamol, orciprenaline and soterenol with those of isoprenaline.

J Pharm Pharmacol. 1970 Dec;22(12):945-7. doi: 10.1111/j.2042-7158.1970.tb08481.x.

New class of selective stimulants of beta-adrenergic receptors.

Nature. 1968 Aug 24;219(5156):861-2. doi: 10.1038/219861a0.

[Beta-sympathomimetic effect of d- and 1-Clorprenaline in normal and reserpinized dogs].

Arzneimittelforschung. 1970 Nov;20(11):1738-41.

Some pharmacological properties of terbutaline (INN), 1-(3,5-dihydroxyphenyl)-2-(T-butylamino)-ethanol. A new sympathomimetic beta-receptor-stimulating agent.

Acta Med Scand Suppl. 1970;512:11-9. doi: 10.1111/j.0954-6820.1970.tb05284.x.

引用本文的文献

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra-Long-Acting β-Agonists Used for Asthma and COPD.

Pharmacol Res Perspect. 2025 Oct;13(5):e70154. doi: 10.1002/prp2.70154.

Adrenoceptors: Receptors, Ligands and Their Clinical Uses, Molecular Pharmacology and Assays.

Handb Exp Pharmacol. 2024;285:55-145. doi: 10.1007/164_2024_713.

Asthma and COPD: A Focus on β-Agonists - Past, Present and Future.

Handb Exp Pharmacol. 2024;285:369-451. doi: 10.1007/164_2023_679.

β Agonists.

Handb Exp Pharmacol. 2017;237:23-40. doi: 10.1007/164_2016_64.

Sympathomimetic bronchodilators: increased selectivity with lung-specific prodrugs.

Pharm Res. 1985 Jul;2(4):156-62. doi: 10.1023/A:1016379820412.

Agonizing over agonism: should asthmatics turn their beta-receptors on or off?

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2095-6. doi: 10.1073/pnas.0812935106. Epub 2009 Feb 11.

Drugs for asthma.

Br J Pharmacol. 2006 Jan;147 Suppl 1(Suppl 1):S297-303. doi: 10.1038/sj.bjp.0706437.

Regulation of the expression of the proenkephalin gene in cultured meningeal fibroblasts: opposite effects of alpha 1- and beta 2-adrenoceptors.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Oct;354(4):404-10. doi: 10.1007/BF00168429.

The selectivity of beta-adrenoceptor antagonists on isoprenaline-induced changes in heart rate, blood pressure, soleus muscle contractility and airways function in anaesthetized cats.

Br J Pharmacol. 1983 Oct;80(2):323-34. doi: 10.1111/j.1476-5381.1983.tb10037.x.

Interaction of beta-adrenoceptor agonists with the serotonergic system in rat brain. A behavioral study using the L-5-HTP syndrome.

Naunyn Schmiedebergs Arch Pharmacol. 1981 Jun;316(3):225-30. doi: 10.1007/BF00505653.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha 1,alpha 3-diol (AH.3365): a selective beta-adrenergic stimulant.

作者信息

Brittain R T, Farmer J B, Jack D, Martin L E, Simpson W T

出版信息

Nature. 1968 Aug 24;219(5156):862-3. doi: 10.1038/219862a0.

DOI:10.1038/219862a0

PMID:5673352

Abstract

摘要

相似文献

Alpha-[(t-Butylamino)methyl]-4-hydroxy-m-xylene-alpha 1,alpha 3-diol (AH.3365): a selective beta-adrenergic stimulant.

Nature. 1968 Aug 24;219(5156):862-3. doi: 10.1038/219862a0.

3-(Alpha-(tert-butylamino)methyl)-5-hydroxy-m-xylene-alpha, alpha'-diol, a selective bronchodilator.

J Med Chem. 1974 Oct;17(10):1112-5. doi: 10.1021/jm00256a017.

A comparison of the beta-adrenoreceptor stimulant properties of isoprenaline, with those of orciprenaline, salbutamol, soterenol and trimetoquinol on isolated atria and trachea of the guinea pig.

J Pharm Pharmacol. 1970 Jan;22(1):61-3. doi: 10.1111/j.2042-7158.1970.tb08388.x.

The bronchodilator and cardiac stimulant effects of Thll65a, salbutamol and isoproterenol.

J Pharmacol Exp Ther. 1973 Sep;186(3):472-81.

The effect of isopropylamino radical on the cardiovascular system.

Jpn Circ J. 1968 Mar;32(3):341-6. doi: 10.1253/jcj.32.341.

An examination of some -adrenoreceptor stimulants for selectivity using the isolated trachea and atria of the guinea pig.

Eur J Pharmacol. 1972 Sep;19(3):371-9. doi: 10.1016/0014-2999(72)90104-5.

A comparison of the beta-adrenoceptor stimulant properties of salbutamol, orciprenaline and soterenol with those of isoprenaline.

J Pharm Pharmacol. 1970 Dec;22(12):945-7. doi: 10.1111/j.2042-7158.1970.tb08481.x.

New class of selective stimulants of beta-adrenergic receptors.

Nature. 1968 Aug 24;219(5156):861-2. doi: 10.1038/219861a0.

[Beta-sympathomimetic effect of d- and 1-Clorprenaline in normal and reserpinized dogs].

Arzneimittelforschung. 1970 Nov;20(11):1738-41.

Some pharmacological properties of terbutaline (INN), 1-(3,5-dihydroxyphenyl)-2-(T-butylamino)-ethanol. A new sympathomimetic beta-receptor-stimulating agent.

Acta Med Scand Suppl. 1970;512:11-9. doi: 10.1111/j.0954-6820.1970.tb05284.x.

引用本文的文献

A Comparison of the Molecular Pharmacological Properties of Current Short, Long, and Ultra-Long-Acting β-Agonists Used for Asthma and COPD.

Pharmacol Res Perspect. 2025 Oct;13(5):e70154. doi: 10.1002/prp2.70154.

Adrenoceptors: Receptors, Ligands and Their Clinical Uses, Molecular Pharmacology and Assays.

Handb Exp Pharmacol. 2024;285:55-145. doi: 10.1007/164_2024_713.

Asthma and COPD: A Focus on β-Agonists - Past, Present and Future.

Handb Exp Pharmacol. 2024;285:369-451. doi: 10.1007/164_2023_679.

β Agonists.

Handb Exp Pharmacol. 2017;237:23-40. doi: 10.1007/164_2016_64.

Sympathomimetic bronchodilators: increased selectivity with lung-specific prodrugs.

Pharm Res. 1985 Jul;2(4):156-62. doi: 10.1023/A:1016379820412.

Agonizing over agonism: should asthmatics turn their beta-receptors on or off?

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2095-6. doi: 10.1073/pnas.0812935106. Epub 2009 Feb 11.

Drugs for asthma.

Br J Pharmacol. 2006 Jan;147 Suppl 1(Suppl 1):S297-303. doi: 10.1038/sj.bjp.0706437.

Regulation of the expression of the proenkephalin gene in cultured meningeal fibroblasts: opposite effects of alpha 1- and beta 2-adrenoceptors.

Naunyn Schmiedebergs Arch Pharmacol. 1996 Oct;354(4):404-10. doi: 10.1007/BF00168429.

The selectivity of beta-adrenoceptor antagonists on isoprenaline-induced changes in heart rate, blood pressure, soleus muscle contractility and airways function in anaesthetized cats.

Br J Pharmacol. 1983 Oct;80(2):323-34. doi: 10.1111/j.1476-5381.1983.tb10037.x.

Interaction of beta-adrenoceptor agonists with the serotonergic system in rat brain. A behavioral study using the L-5-HTP syndrome.

Naunyn Schmiedebergs Arch Pharmacol. 1981 Jun;316(3):225-30. doi: 10.1007/BF00505653.