Hendrix J W, Guttman S M
Science. 1968 Sep 20;161(3847):1252. doi: 10.1126/science.161.3847.1252.
Estradiol prevented cholesterol-induced sexual reproduction by the fungus Pythium periplocum. Inhibition by estradiol was partial at 10-(6)M and complete at 10-(5)M, the same concentrations at which cholesterol and beta-sitosterol were initially and maximally active. Higher concentrations of estradiol were required for growth inhibition than for inhibition of reproduction.
雌二醇可防止真菌围小丛壳菌因胆固醇诱导的有性繁殖。在10⁻⁶M时，雌二醇的抑制作用是部分性的，而在10⁻⁵M时则完全抑制，这与胆固醇和β-谷甾醇最初发挥最大活性时的浓度相同。与抑制繁殖相比，抑制生长需要更高浓度的雌二醇。
