Browse N L, Thomas M L, Pim H P
Br Med J. 1968 Sep 21;3(5620):717-20. doi: 10.1136/bmj.3.5620.717.
Five patients with deep vein thrombosis were given streptokinase. Five others with similar phlebograms were given anticoagulants, and the results assessed by examining changes in the iliac, femoral, and calf segments of the phlebograms when repeated 7-10 days later. Those of the anticoagulant group were unchanged. Four of the five given streptokinase had a reduction in the size and extent of their thrombosis. Fresh thrombus surrounded by flowing blood was lysed. Thrombus completely blocking a vein was not lysed.The indications for the use of streptokinase in deep vein thrombosis are reviewed.
五名深静脉血栓患者接受了链激酶治疗。另外五名静脉造影表现相似的患者接受了抗凝剂治疗，并在7 - 10天后重复检查时通过观察静脉造影的髂部、股部和小腿段变化来评估结果。抗凝剂组的结果没有变化。接受链激酶治疗的五名患者中有四名血栓的大小和范围有所减小。被流动血液包围的新鲜血栓被溶解。完全阻塞静脉的血栓未被溶解。本文对链激酶在深静脉血栓治疗中的应用指征进行了综述。
