Bockrath R, Person S, Funk F
Biophys J. 1968 Sep;8(9):1027-36. doi: 10.1016/S0006-3495(68)86536-1.
Transmutation of the radioisotope tritium occurs with the production of a low energy electron, having a range in biological material similar to the dimensions of a bacterium. A computer program was written to determine the radiation dose distributions which may be expected within a bacterium as a result of tritium decay, when the isotope has been incorporated into specific regions of the bacterium. A nonspherical model bacterium was used, represented by a cylinder with hemispherical ends. The energy distributions resulting from a wide variety of simulated labeled regions were determined; the results suggested that the nuclear region of a bacterium receives on the average significantly different per decay doses, if the labeled regions were those conceivably produced by the incorporation of thymidine-(3)H, uracil-(3)H, or (3)H-amino acids. Energy distributions in the model bacterium were also calculated for the decay of incorporated (14)carbon, (35)sulfur, and (32)phosphorous.
放射性同位素氚的嬗变会产生低能电子，其在生物材料中的射程与细菌的尺寸相近。编写了一个计算机程序，以确定当该同位素已掺入细菌的特定区域时，由于氚衰变，细菌内部可能预期的辐射剂量分布。使用了一个非球形模型细菌，由两端为半球形的圆柱体表示。确定了各种模拟标记区域产生的能量分布；结果表明，如果标记区域是由掺入胸腺嘧啶 -（3）H、尿嘧啶 -（3）H 或（3）H - 氨基酸可能产生的，那么细菌的核区域每衰变剂量平均会有显著差异。还计算了掺入的（14）碳、（35）硫和（32）磷衰变时模型细菌中的能量分布。
