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由掺入细菌中的氚及其他放射性同位素衰变所计算出的能量沉积。

Calculated energy deposits from the decay of tritium and other radioisotopes incorporated into bacteria.

作者信息

Bockrath R, Person S, Funk F

出版信息

Biophys J. 1968 Sep;8(9):1027-36. doi: 10.1016/S0006-3495(68)86536-1.

Abstract

Transmutation of the radioisotope tritium occurs with the production of a low energy electron, having a range in biological material similar to the dimensions of a bacterium. A computer program was written to determine the radiation dose distributions which may be expected within a bacterium as a result of tritium decay, when the isotope has been incorporated into specific regions of the bacterium. A nonspherical model bacterium was used, represented by a cylinder with hemispherical ends. The energy distributions resulting from a wide variety of simulated labeled regions were determined; the results suggested that the nuclear region of a bacterium receives on the average significantly different per decay doses, if the labeled regions were those conceivably produced by the incorporation of thymidine-(3)H, uracil-(3)H, or (3)H-amino acids. Energy distributions in the model bacterium were also calculated for the decay of incorporated (14)carbon, (35)sulfur, and (32)phosphorous.

摘要

放射性同位素氚的嬗变会产生低能电子,其在生物材料中的射程与细菌的尺寸相近。编写了一个计算机程序,以确定当该同位素已掺入细菌的特定区域时,由于氚衰变,细菌内部可能预期的辐射剂量分布。使用了一个非球形模型细菌,由两端为半球形的圆柱体表示。确定了各种模拟标记区域产生的能量分布;结果表明,如果标记区域是由掺入胸腺嘧啶 -(3)H、尿嘧啶 -(3)H 或(3)H - 氨基酸可能产生的,那么细菌的核区域每衰变剂量平均会有显著差异。还计算了掺入的(14)碳、(35)硫和(32)磷衰变时模型细菌中的能量分布。

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本文引用的文献

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THE CALCULATION OF RADIATION DOSE FROM DISTRIBUTED SOURCES OF TRITIUM.来自分布式氚源的辐射剂量计算
Int J Radiat Biol Relat Stud Phys Chem Med. 1964;8:545-9. doi: 10.1080/09553006414550691.
8
High resolution autoradiography of bacteria labelled with tritiated uridine.
J Mol Biol. 1965 Dec;14(2):623-5. doi: 10.1016/s0022-2836(65)80216-9.
9
10
Evidence for two geometrically distinct targets mediating arginine reversion in E. coli.
Mutat Res. 1967 Nov-Dec;4(6):871-3. doi: 10.1016/0027-5107(67)90095-4.

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