Levina L A, Vartanian Iu P, Chuliĭ G A, Beĭlina V B
Zh Mikrobiol Epidemiol Immunobiol. 1978 Jul(7):104-7.
Opsonizing activity of guinea pig blood serum containing mercaptoethanol-resistant pertussis antibodies was studied in vitro on a model of microorganism ingestion by the mononuclears of the guinea pig peritoneal exudate. There were revealed distinct differences in the serum activity depending on the phagocytosis object. The blood serum of hyperimmunized rabbits stimulated the ingestion of Bordetella pertussis by mononuclears of guinea pigs--normal and immunized with pertussis vaccine. The blood sera of hyperimmunized guinea pigs and of mice immunized with pertussis vaccine twice displayed opsonins to B. pertussis. The blood sera of animals immunized with pertussis vaccine inhibited the staphylococcus ingestion by the peritoneal exudate mononuclears of guinea pigs, both normal and those immunized with pertussis vaccine.
在豚鼠腹腔渗出液单核细胞摄取微生物的模型上，体外研究了含有巯基乙醇抗性百日咳抗体的豚鼠血清的调理活性。结果发现，血清活性因吞噬对象不同而存在明显差异。高度免疫兔子的血清能刺激正常和接种百日咳疫苗的豚鼠单核细胞摄取百日咳博德特菌。高度免疫豚鼠和两次接种百日咳疫苗的小鼠的血清对百日咳博德特菌表现出调理素活性。接种百日咳疫苗的动物血清抑制正常和接种百日咳疫苗的豚鼠腹腔渗出液单核细胞摄取葡萄球菌。
