Deverall P B, Wooler G H
Thorax. 1968 Sep;23(5):537-40. doi: 10.1136/thx.23.5.537.
A case of chronic sternal sinus is described in which exploration revealed a loose patch of Teflon felt which had been used three years earlier in reconstructing the outflow tract of the right ventricle in a case of congenital pulmonary stenosis. Teflon, a synthetic polymer of low biological reactivity, while being suitable in its solid sheet form for use in plastic reconstructive surgery, is not ideally suited to cardiovascular work. The properties of such an ideal material are defined. The low reactivity and porosity of Teflon, by reducing fibroblastic invasion, lessens the likelihood of the material being incorporated by host tissues. From experimental and clinical evidence we no longer regard Teflon felt as a suitable prosthetic material for use in intracardiac or vascular work or in reconstruction of the right ventricular outflow tract.
本文描述了一例慢性胸骨窦病例，术中探查发现一块松散的特氟龙毡片，该毡片在三年前用于一名先天性肺动脉狭窄患者右心室流出道重建。特氟龙是一种生物反应性低的合成聚合物，虽然其固体片状形式适用于整形重建手术，但并不完全适合心血管手术。文中定义了这种理想材料的特性。特氟龙的低反应性和孔隙率通过减少成纤维细胞浸润，降低了该材料被宿主组织整合的可能性。根据实验和临床证据，我们不再认为特氟龙毡片是用于心内或血管手术或右心室流出道重建的合适假体材料。
