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[白血病患者血液制品的抗原诱导活性]

[Antigen-inducing activity of blood preparations from leukemia patients].

作者信息

Kokosha L V, Ivanov M T, Lapin B A, Iakovleva L A

出版信息

Vopr Virusol. 1976 Jan-Feb(1):12-8.

PMID:56813
Abstract

The evidence of appearance of specific surface antigen in the blood leukocytes of monkeys inoculated with cell-containing or cell-free materials from patients with leukemia (different variants of acute leukemia, chronic myelo- and lympholeukemia) with various clinicohematological characteristics is presented. The results of comparisons of the electron microscope and immunofluorescent examinations of experimental and control monkeys showed that the majority of the experimental animals with positive immunofluorescent tests were shown by the electron microscope examinations to have virus particles type C.

摘要

本文展示了用患有白血病(不同类型的急性白血病、慢性粒细胞白血病和淋巴细胞白血病)且具有各种临床血液学特征的患者的含细胞或无细胞材料接种的猴子的血液白细胞中出现特定表面抗原的证据。对实验猴和对照猴进行电子显微镜和免疫荧光检查的比较结果表明,大多数免疫荧光检测呈阳性的实验动物经电子显微镜检查显示含有C型病毒颗粒。

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