针对人类淋巴细胞和髓细胞白血病细胞的抗原：用非人类灵长类动物抗血清进行检测。
Antigens specific for human lymphocytic and myeloid leukemia cells: detection by nonhuman primate antiserums.
作者信息
Metzgar R S, Mohanakumar T, Miller D S
出版信息
Science. 1972 Dec 1;178(4064):986-8. doi: 10.1126/science.178.4064.986.
PMID:4628523
Abstract
Primate antiserums to human leukemia cells can detect antigens specific for lymphocytic leukemia cells or antigens present on certain myeloid leukemia cells. The antigen specific for lymphocytic leukemia cells is destroyed by treatment with neuraminidase or trypsin. Tryptic digests of lymphocytic leukemia cells contain the antigen, which has a high molecular weight.
摘要
针对人类白血病细胞的灵长类动物抗血清能够检测出淋巴细胞白血病细胞特有的抗原或某些髓细胞白血病细胞上存在的抗原。淋巴细胞白血病细胞特有的抗原经神经氨酸酶或胰蛋白酶处理后会被破坏。淋巴细胞白血病细胞的胰蛋白酶消化产物含有该抗原，其分子量很高。
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