Heyne K, Dörner K, Graucob E, Wiedemann H R
Klin Padiatr. 1978 Nov;190(6):576-9.
In one case of Menkes' Syndrome (Trichopoliodystrophy), a monophylic vacuolisation of myeloic cells (promyelocytes) of the bone marrow was observed. This finding correlates with an identical observation reported in medical literature, as well as with vacuolisations of metabolic active cells of the brain, musculature and skin observed in patients suffering from this disease. In the present paper, this finding is interpreted as an expression of the underlying disease and of the deficiency of oxidative cell ferment systems, and is discussed as a possible diagnostic and therapeutic criterion.
在一例门克斯综合征（毛发硫营养不良）中，观察到骨髓中髓样细胞（早幼粒细胞）出现单系空泡化。这一发现与医学文献中报道的相同观察结果相关，也与该疾病患者大脑、肌肉组织和皮肤中代谢活跃细胞的空泡化相关。在本文中，这一发现被解释为潜在疾病和氧化细胞发酵系统缺陷的一种表现，并作为一种可能的诊断和治疗标准进行了讨论。
