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[所谓迟发性癫痫(作者译)]

[So-called late epilepsy (author's transl)].

作者信息

Neundörfer B, Meyer-Wahl L, Meyer J G, Bals E, Bals R

出版信息

Wien Klin Wochenschr. 1978 Nov 10;90(21):765-72.

PMID:568852
Abstract

411 patients with epileptic seizures manifest only after the age of 25 were investigated as to aetiology, seizure type and frequency and age and sex distribution. Neurological, neuro-radiological and EEG findings are reported: There was a clear prevalence of male patients (67%). Manifestation occurred mainly between 30 and 40 years of age (65%). Most seizures were primarily of the generalized grand mal type (68%). Grand mal with focal onset occurred in 13%, partial seizures in 11%, complex partial seizures (psychomotor seizures) in 5%, the latter plus grand mal seizures in 2% and other types in 1% of the cases. Aetiological factors were: chronic alcoholism (31%), vascular diseases (17%), tumours (12%), traumatic brain lesions (8,5%), toxic metabolic lesions (6%) and other factors (6%). Idiopathic epilepsy of late onset was a rare cause (4%). The aetiology remained unknown in 15% of cases. We found that the differences in age distribution, seizure type and the EEG findings are significant factors in the differential diagnosis and we compared them with those found in similar investigations.

摘要

对411例25岁以后才出现癫痫发作的患者进行了病因、发作类型及频率以及年龄和性别分布的调查。报告了神经学、神经放射学和脑电图检查结果:男性患者明显居多(67%)。发作主要发生在30至40岁之间(65%)。大多数发作主要为全身性大发作类型(68%)。局灶性起病的大发作占13%,部分性发作占11%,复杂部分性发作(精神运动性发作)占5%,后者合并大发作占2%,其他类型占1%。病因包括:慢性酒精中毒(31%)、血管疾病(17%)、肿瘤(12%)、颅脑外伤(8.5%)、中毒代谢性损害(6%)和其他因素(6%)。迟发性特发性癫痫是一种罕见病因(4%)。15%的病例病因不明。我们发现年龄分布、发作类型和脑电图检查结果的差异是鉴别诊断中的重要因素,并将它们与类似研究中的发现进行了比较。

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