• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

外感受性刺激对泌乳大鼠排乳的影响。

The effect of an exteroceptive stimulus on milk ejection in lactating rats.

作者信息

Deis R P

出版信息

J Physiol. 1968 Jul;197(1):37-46. doi: 10.1113/jphysiol.1968.sp008543.

DOI:10.1113/jphysiol.1968.sp008543
PMID:5691944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1351782/
Abstract
  1. The exteroceptive stimulus emanating from a lactating rat and the litter while suckling was used to induce milk ejection in another lactating mother 15 min before the replacement of her own litter. The effect of the external stimulus on milk ejection during one 30 min period and four 15 min periods of nursing was studied.2. After being isolated for 9 hr the litter from the mother subjected to the exteroceptive nursing stimulus (induced rat) obtained a significantly greater amount of milk during 30 min of nursing than that obtained by the litter from the control mother.3. When deaf mother rats were used the gain of milk by the litter showed no difference between the control and the induced mother. This result indicated that the effective external stimulus is an auditory one and is probably produced by the mother rat and the young while suckling.4. The administration of oxytocin (Syntocinon, Sandoz) 20 m-u./100 g body wt., 15 min before the replacement of the litter produced a milk ejection similar to that obtained under the influence of the auditory stimulus. This would indicate that the exteroceptive stimulus probably evokes the release of oxytocin from the neurohypophysis.5. When nursing was performed in four periods of 15 min each the litter of the control mother obtained milk only in the second period of nursing while the litter of the induced mother obtained milk in all four periods of nursing and the amount of milk obtained in the whole hour was greater than that from the control rat.6. The administration of oxytocin just before the replacement of the litter every 15 min produced milk ejection only in the first two periods of suckling in the control rats but the induced rats were capable of ejecting milk during all four periods.7. The most satisfactory conclusion for the results obtained is that the C.N.S. regulates both the release of oxytocin in response to suckling and the response of the mammary gland to oxytocin, in the lactating rat.
摘要

  1. 在替换自己的幼崽前15分钟，用正在哺乳的大鼠及其幼崽发出的外感受性刺激，来诱导另一只正在哺乳的母鼠排乳。研究了外部刺激在一个30分钟哺乳期和四个15分钟哺乳期内对排乳的影响。

  2. 接受外感受性哺乳刺激的母鼠（诱导大鼠）的幼崽在隔离9小时后，在30分钟的哺乳期内获得的乳汁量显著多于对照母鼠的幼崽。

  3. 当使用失聪的母鼠时，对照母鼠和诱导母鼠的幼崽所获乳汁量没有差异。这一结果表明，有效的外部刺激是听觉刺激，可能由母鼠和幼崽在哺乳时发出。

  4. 在替换幼崽前15分钟，按每100克体重注射20毫微克催产素（合成催产素，山德士公司），可产生与听觉刺激影响下相似的排乳效果。这表明外感受性刺激可能促使神经垂体释放催产素。

  5. 当哺乳分为四个15分钟的时段进行时，对照母鼠的幼崽仅在第二个哺乳时段获得乳汁，而诱导母鼠的幼崽在所有四个哺乳时段都能获得乳汁，且整个小时内获得的乳汁量多于对照大鼠。

  6. 在每次替换幼崽前15分钟注射催产素，对照大鼠仅在前两个哺乳时段出现排乳，但诱导大鼠在所有四个时段都能排乳。

  7. 对所获结果最合理的结论是，在哺乳期大鼠中，中枢神经系统既调节因哺乳而产生的催产素释放，也调节乳腺对催产素的反应。

相似文献

1
The effect of an exteroceptive stimulus on milk ejection in lactating rats.外感受性刺激对泌乳大鼠排乳的影响。
J Physiol. 1968 Jul;197(1):37-46. doi: 10.1113/jphysiol.1968.sp008543.
2
The effect of an exteroceptive stimulus on the concentration of melanocyte-stimulating hormone in the pituitary of lactating rats.外部感受性刺激对泌乳期大鼠垂体中促黑素细胞激素浓度的影响。
J Physiol. 1968 Jul;197(1):47-51. doi: 10.1113/jphysiol.1968.sp008544.
3
Inhibition of milk ejection by a visual stimulus in lactating rats: implication of the pineal gland.
Brain Res. 1982 Nov 18;251(2):313-8. doi: 10.1016/0006-8993(82)90748-x.
4
The milk ejection reflex in the pig.猪的排乳反射。
J Physiol. 1982 Dec;333:577-94. doi: 10.1113/jphysiol.1982.sp014470.
5
Participation of the hippocampus in the facilitatory effect of an exteroceptive stimulus on milk ejection.海马体在外感受性刺激对排乳的促进作用中的参与。
Exp Brain Res. 1984;55(1):177-9. doi: 10.1007/BF00240513.
6
Inhibitory effect of prostaglandin F2 alpha on oxytocin release and on milk ejection in lactating rats.前列腺素F2α对泌乳大鼠催产素释放及排乳的抑制作用。
J Endocrinol. 1976 Jun;69(3):395-9. doi: 10.1677/joe.0.0690395.
7
Changing characteristics of the milk-ejection reflex during pregnancy, lactation and after weaning in the rat.大鼠在怀孕、哺乳及断奶后泌乳反射的变化特征
J Reprod Fertil. 1986 Jan;76(1):123-30. doi: 10.1530/jrf.0.0760123.
8
Effect of 2,4-dichlorophenoxyacetic acid on milk transfer to the litter and prolactin release in lactating rats.2,4-二氯苯氧乙酸对泌乳大鼠乳转移和催乳素分泌的影响。
Toxicology. 2010 Apr 30;271(1-2):13-20. doi: 10.1016/j.tox.2010.01.016. Epub 2010 Feb 1.
9
Sleep: a prerequisite for reflex milk ejection in the rat.睡眠：大鼠反射性排乳的一个前提条件。
Exp Brain Res. 1980 Jan;38(2):151-62. doi: 10.1007/BF00236736.
10
Effect of L-dopa on milk ejection and prolactin release in lactating rats.左旋多巴对泌乳大鼠排乳及催乳素释放的影响。
J Endocrinol. 1975 Dec;67(3):397-401. doi: 10.1677/joe.0.0670397.

引用本文的文献

1
Mammary gland sympathetic innervation is a major component in type 1 deiodinase regulation.乳腺交感神经支配是1型脱碘酶调节的主要组成部分。
Endocrine. 1999 Oct;11(2):115-21. doi: 10.1385/ENDO:11:2:115.
2
Milk yield, suckling behaviour and milk ejection in the lactating rat nursing litters of different sizes.哺乳期大鼠哺育不同大小窝仔时的产奶量、哺乳行为及乳汁排出情况。
J Physiol. 1980 Jun;303:403-15. doi: 10.1113/jphysiol.1980.sp013295.
3
Participation of the hippocampus in the facilitatory effect of an exteroceptive stimulus on milk ejection.海马体在外感受性刺激对排乳的促进作用中的参与。
Exp Brain Res. 1984;55(1):177-9. doi: 10.1007/BF00240513.
4
The effect of an exteroceptive stimulus on the concentration of melanocyte-stimulating hormone in the pituitary of lactating rats.外部感受性刺激对泌乳期大鼠垂体中促黑素细胞激素浓度的影响。
J Physiol. 1968 Jul;197(1):47-51. doi: 10.1113/jphysiol.1968.sp008544.

本文引用的文献

1
Neurohormonal mechanisms in emotional inhibition of milk ejection.情绪性抑制乳汁排出的神经激素机制。
J Endocrinol. 1955 Jan;12(1):29-37. doi: 10.1677/joe.0.0120029.
2
EVIDENCE THAT EXTEROCEPTIVE STIMULI CAN RELEASE PROLACTIN FROM THE PITUITARY GLAND OF THE LACTATING RAT.关于外感受性刺激能促使泌乳大鼠垂体释放催乳素的证据。
Endocrinology. 1965 Feb;76:340-2. doi: 10.1210/endo-76-2-340.
3
INFLUENCE OF CEREBRAL CORTEX IN INHIBITION OF OXYTOCIN RELEASE INDUCED BY STRESSFUL STIMULI.
Am J Physiol. 1964 Dec;207:1394-8. doi: 10.1152/ajplegacy.1964.207.6.1394.
4
A method for evaluation of milk "let-down" in lactating rat.一种评估泌乳大鼠乳汁“排出”的方法。
Proc Soc Exp Biol Med. 1957 Apr;94(4):816-7. doi: 10.3181/00379727-94-23098.
5
Sympathetico-adrenal inhibition of the neurohypophysial milk-ejection mechanism.交感肾上腺对神经垂体排乳机制的抑制作用。
J Endocrinol. 1953 Jan;9(1):7-18.
6
Effect of auditory, olfactory and optic stimuli upon milk ejection and suckling-induced release of prolactin in lactating rats.听觉、嗅觉和视觉刺激对泌乳大鼠乳汁排出及吮乳诱导的催乳素释放的影响。
Endocrinology. 1967 May;80(5):840-6. doi: 10.1210/endo-80-5-840.
7
The release of neurohypophysial hormone by sound.声音刺激引起神经垂体激素释放。
J Endocrinol. 1966 Nov;36(3):281-90. doi: 10.1677/joe.0.0360281.