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对受刺激的电鳐电器官神经末梢中乙酰胆碱释放及波动的定量描述。

Quantitative description of acetylcholine release and fluctuations in nerve terminals of torpedo electric organ submitted to stimulation.

作者信息

Israel M, Lesbats B, Manaranche R

出版信息

Pflugers Arch. 1978 Oct 18;377(1):117-8. doi: 10.1007/BF00584383.

DOI:10.1007/BF00584383
PMID:569277
Abstract

A model, considering cytoplasmic ACh as the difference between cumulated outputs per impulse, and synthesized ACh leads to simple equations correlating biochemical and electrical measurables. Intrinsic properties of the release mechanism are deduced.

摘要

一个模型，将细胞质乙酰胆碱视为每个冲动累积输出量之间的差异，并且合成的乙酰胆碱会得出将生化和电学可测量值关联起来的简单方程。由此推导出释放机制的内在特性。

相似文献

1
Quantitative description of acetylcholine release and fluctuations in nerve terminals of torpedo electric organ submitted to stimulation.对受刺激的电鳐电器官神经末梢中乙酰胆碱释放及波动的定量描述。
Pflugers Arch. 1978 Oct 18;377(1):117-8. doi: 10.1007/BF00584383.
2
Seasonal variations in the muscarinic regulation of acetylcholine release from Torpedo electric organ nerve terminals.
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;81(2):439-44. doi: 10.1016/0742-8413(85)90034-9.
3
Biochemical evidence that acetylcholine release from cholinergic nerve terminals is mostly vesicular.生物化学证据表明，胆碱能神经末梢释放的乙酰胆碱大多是通过囊泡进行的。
FEBS Lett. 1985 Sep 2;188(2):389-93. doi: 10.1016/0014-5793(85)80408-7.
4
Incorporation of acetate into acetylcholine, acetylcarnitine, and amino acids in the Torpedo electric organ.乙酸盐掺入电鳐电器官中的乙酰胆碱、乙酰肉碱和氨基酸。
J Neurochem. 1985 Dec;45(6):1809-19. doi: 10.1111/j.1471-4159.1985.tb10538.x.
5
Oscillation of acetylcholine during nerve activity in the Torpedo electric organ.
Brain Res. 1977 Apr 8;125(1):123-40. doi: 10.1016/0006-8993(77)90364-x.
6
Acetylcholine changes underlying transmission of a single nerve impulse in the presence of 4-aminopyridine in Torpedo.在电鳐中，乙酰胆碱在4-氨基吡啶存在的情况下改变单个神经冲动的传递基础。
J Physiol. 1982 Apr;325:461-79. doi: 10.1113/jphysiol.1982.sp014162.
7
Cetiedil, a drug that inhibits acetylcholine release in Torpedo electric organ.
J Neurochem. 1987 Aug;49(2):548-54. doi: 10.1111/j.1471-4159.1987.tb02899.x.
8
Cholinergic inhibition of acetylcholine release in the electric organ of Torpedo.
Eur J Pharmacol. 1982 Feb 26;78(2):201-12. doi: 10.1016/0014-2999(82)90237-0.
9
Pulsatile release of acetylcholine by nerve terminals (synaptosomes) isolated from Torpedo electric organ.从电鳐电器官分离出的神经末梢（突触体）对乙酰胆碱的脉冲式释放。
J Physiol. 1992 May;450:325-40. doi: 10.1113/jphysiol.1992.sp019129.
10
Opiates inhibit acetylcholine release from Torpedo nerve terminals by blocking Ca2+ influx.
J Neurochem. 1984 Sep;43(3):614-8. doi: 10.1111/j.1471-4159.1984.tb12779.x.

本文引用的文献

1
Multimodal distribution of frog miniature endplate potentials in adult denervated and tadpole leg muscle.成年去神经青蛙和蝌蚪腿部肌肉中蛙微小终板电位的多峰分布
J Gen Physiol. 1974 Jul;64(1):85-103. doi: 10.1085/jgp.64.1.85.
2
Loss of vesicular acetycholine in the Torpedo electric organ on discharge against high external resistance.
J Neurochem. 1976 Oct;27(4):975-7. doi: 10.1111/j.1471-4159.1976.tb05166.x.
3
Oscillation of acetylcholine during nerve activity in the Torpedo electric organ.
Brain Res. 1977 Apr 8;125(1):123-40. doi: 10.1016/0006-8993(77)90364-x.
4
Proceedings: Periodic fluctuations in transmitter release at the frog neuromuscular junction.论文集：青蛙神经肌肉接头处递质释放的周期性波动
J Physiol. 1976 Mar;256(1):20P-21P.